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Mouse recombinant IL22
Mouse recombinant IL22
  PRSI92-663
 :  
Mouse recombinant IL22
  PRSI92-663
 :  

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  • Pk:
    50 µG
  • Protein/peptide type:
    Recombinant
  • Species:
    Mouse
  • Tag sequence:
    C-mFc tag
  • Storage conditions:
    Lyophilized protein should be stored at −20 °C, though stable at room temperature for 3 weeks. Reconstituted protein solution can be stored at 4-7 °C for 2-7 days. Aliquots of reconstituted samples are stable at −20 °C for 3 months.
  • Protein synonyms:
    IL-TIF|IL-22|IL-TIF alpha|IL-22a|Interleukin-22a|IL-10-related T-cell-derived-inducible factor|IL22|Interleukin-22
  • Protein/peptide name:
    IL22
  • Purity:
    > 95% as determined by reducing SDS-PAGE
  • Molecular weight:
    43.8 kD
  • Sequence:
    Leu34-Val179
  • Formulation:
    Lyophilized from a 0.2 um filtered solution of PBS, pH7.4. Always centrifuge tubes before opening. Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100 ug/ml. Dissolve the Lyophilized protein in ddH2O. Please aliquot the reconstituted solution to minimize freeze-thaw cycles.

 

 

Interleukin-22 (IL-22) was initially identified as a gene induced by IL-9 in mouse T cells and mast cells. Mouse IL-22 cDNA encodes a 179 amino acid residue protein with a putative 33 amino acid signal peptide that is cleaved to generate a 147 amino acid mature protein that shares approximately 79% and 22% sequence identity with human IL22 and IL10, respectively. IL22 has been shown to activate STAT-1 and STAT-3 in several hepatoma cell lines and up-regulate the production of acute phase proteins. IL-22 is produced by normal mouse T cells upon Con A activation. Mouse IL-22 expression is also induced in various organs upon lipopolysaccharide injection, suggesting that IL-22 may be involved in inflammatory responses. The functional IL-22 receptor complex consists of two receptor subunits, IL-22R (previously an orphan receptor named CRF2-9) and IL-10R beta (previously known as CRF2-4), belonging to the class II cytokine receptor family.

Fusion-Tag: C-mFc tag

This recombinant protein can be used for biological assays. For research use only.