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Specifications
- Pk:50 µG
- Protein/peptide type:Recombinant
- Species:Mouse
- Tag sequence:C-Fc tag
- Storage conditions:Lyophilized protein should be stored at −20 °C, though stable at room temperature for 3 weeks. Reconstituted protein solution can be stored at 4-7 °C for 2-7 days. Aliquots of reconstituted samples are stable at −20 °C for 3 months.
- Protein synonyms:NKRL|CMRF35H|CLM8|CMRF-35-H9CD300 antigen-like family member A|CD300a|MAIR-I|CMRF-35H|CMRF35-H9|IGSF12NK inhibitory receptor|CLM-8|IRC2|IGSF12|leukocyte membrane antigen|LMIR1|Immunoglobulin superfamily member 12|CMRF35-like molecule 8|CD300a molecule|Pigr4|Mcipr1|IRC1/IRC2|CMRF35-H|IRp60|IRC1|CD300a antigenCMRF35H9|CMRF35H leukocyte immunoglobulin-like receptor|CMRF35HIRp60|Inhibitory receptor protein 60
- Protein/peptide name:LMIR1
- Purity:> 95% as determined by reducing SDS-PAGE
- Molecular weight:44.3 kD
- Sequence:Leu28-Arg183
- Formulation:Lyophilized from a 0.2 um filtered solution of 20mM PB, 150mM NaCl, pH 7.4. Always centrifuge tubes before opening. Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100 ug/ml. Dissolve the Lyophilized protein in ddH2O. Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
Specifications
About this item
LMIR1, also termed CD300a, is a type I transmembrane glycoprotein with a single IgV-like extracellular domain and an extended membrane proximal region that links the immunoglobulin (Ig) and transmembrane domains and belongs to the immunoglobulin superfamily. The intracellular domain of LMIR1 contains several immunoreceptor tyrosine-based inhibition motifs (ITIMs). When cross-linked, it will be tyrosine phosphorylated and capable of recruiting tyrosine phosphatases (SHP-1, SHP-2) and inositol polyphosphate 5-phosphatase, SHIP. LMIR1 will regulate mast cell-mediated inflammatory responses. LMIR1 is broadly expressed on myeloid and lymphoid cells, and its expression is differentially regulated depending on the cell type.
- This recombinant protein can be used for biological assays. For research use only.
Fusion-Tag: C-Fc tag
This recombinant protein can be used for biological assays. For research use only.