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Specifications
- Pk:50 µG
- Protein/peptide type:Recombinant
- Source:E. coli
- Species:Human
- Tag sequence:C-6 His tag
- Storage conditions:Store at −20 °C, stable for 6 months after receipt. Please minimize freeze-thaw cycles.
- Protein synonyms:59kDa immunophilin|HSP-binding immunophilin|FK506-binding protein 4|Peptidyl-prolyl cis-trans isomerase FKBP4|FKBP59|Rotamase|51kDa FK506-binding protein|immunophilin FKBP52|FKBP4
- Protein/peptide name:FKBP52
- Purity:> 95% as determined by reducing SDS-PAGE
- Molecular weight:52.8 kD
- Sequence:Met1-Ala459
- Formulation:Supplied as a 0.2 um filtered solution of 20mM Tris,10%glycerol, pH 8.0. Always centrifuge tubes before opening. Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100 ug/ml. Dissolve the lyophilized protein in ddH2O. Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
- Tested applications:Bioassay
Specifications
About this item
FKBP4 act as a regulator of microtubule dynamics by inhibiting MAPT/TAU ability to promote microtubule assembly. FKBP4 may play a role in the intracellular trafficking of heterooligomeric forms of steroid hormone receptors between cytoplasm and nuclear compartments, it also may have a protective role against oxidative stress in mitochondria. The isomerase activity controls neuronal growth cones via regulation of TRPC1 channel opening.
Fusion-Tag: C-6 His tag
This recombinant protein can be used for biological assays. For research use only.