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Specifications
- Pk:50 µG
- Protein/peptide type:Recombinant
- Source:E. coli
- Species:Human
- Tag sequence:C-6 His tag
- Storage conditions:Store at −20 °C, stable for 6 months after receipt. Please minimize freeze-thaw cycles.
- Protein synonyms:MDA9|Melanoma differentiation-associated protein 9|Syntenin-1|SYCL|Scaffold protein Pbp1|Pro-TGF-alpha cytoplasmic domain-interacting protein 18|Syndecan-binding protein 1|SDCBP
- Protein/peptide name:Syntenin 1
- Purity:> 95% as determined by reducing SDS-PAGE
- Molecular weight:33.5 kD
- Sequence:Ser2-Val298
- Formulation:Supplied as a 0.2 um filtered solution of 20mM PB,150mM NaCl,pH7.4. Always centrifuge tubes before opening. Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100 ug/ml. Dissolve the lyophilized protein in ddH2O. Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
- Tested applications:Bioassay
Specifications
About this item
Syntenin-1 is a molecule linking syndecan-mediated signalling to the cytoskeleton. Syntenin-1 is primarily localised to membrane-associated adherens junctions and focal adhesions but also found at the endoplasmic reticulum and nucleus. The syntenin protein contains tandemly repeated PDZ domains that bind the cytoplasmic, C-terminal domains of a variety of transmembrane proteins. Syntenin-1 may affect cytoskeletal-membrane organisation, cell adhesion, protein trafficking, and the activation of transcription factors. It seems to function as an adapter protein, in adherens junctions may function to couple syndecans to cytoskeletal proteins or signalling components. Syntenin-1 seems to couple transcription factor SOX4 to the IL-5 receptor (IL5RA) and play a role in vesicular trafficking.
Fusion-Tag: C-6 His tag
This recombinant protein can be used for biological assays. For research use only.