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Specifications
- Pk:50 µG
- Protein/peptide type:Recombinant
- Source:E. coli
- Species:Human
- Tag sequence:C-6 His, N-T7 tag
- Storage conditions:Lyophilized protein should be stored at −20 °C, though stable at room temperature for 3 weeks. Reconstituted protein solution can be stored at 4-7 °C for 2-7 days. Aliquots of reconstituted samples are stable at −20 °C for 3 months.
- Protein synonyms:VICKZ Family Member 2|IGF2BP2|VICKZ2|IMP2|IMP-2|IGF-II mRNA-Binding Protein 2|IGF2 mRNA-Binding Protein 2|Hepatocellular Carcinoma Autoantigen p62|Insulin-like Growth Factor 2 mRNA-Binding Protein 2
- Protein/peptide name:IGF2 mRNA-Binding 2
- Purity:> 95% as determined by reducing SDS-PAGE
- Molecular weight:27.2 kD
- Sequence:Met1-Thr220
- Formulation:Lyophilized from a 0.2 um filtered solution of 20mM PB,150mM NaCl,pH7.4. Always centrifuge tubes before opening. Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100 ug/ml. Dissolve the Lyophilized protein in ddH2O. Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
- Tested applications:Bioassay
Specifications
About this item
Insulin-Like Growth Factor 2 mRNA-Binding Protein 2 (IGFBP2) belongs to the RRM IMP/VICKZ family. IGFBP2 is a cytoplasmic protein and contains four KH domains and two RRM (RNA recognition motif) domains. IGF2BP2 binds to the 5'-UTR of the Insulin-Like Growth Factor 2 (IGF2) mRNA. This binding is isoform-specific. IGF2BP2 may regulate translation of target mRNAs. Genetic variation at the IGF2BP2 gene has been associated with type 2 diabetes (T2D) by genome-wide association studies and by replication analyses.
- This recombinant protein can be used for biological assays. For research use only.
Fusion-Tag: C-6 His, N-T7 tag