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Specifications
- Pk:50 µG
- Protein/peptide type:Recombinant
- Source:E. coli
- Species:Human
- Tag sequence:C-6 His, N-T7 tag
- Storage conditions:Store at −20 °C, stable for 6 months after receipt. Please minimize freeze-thaw cycles.
- Protein synonyms:Ubiquitin-like-Conjugating Enzyme ATG10|Autophagy-Related Protein 10|APG10-like|ATG10
- Protein/peptide name:Autophagy 10
- Purity:> 95% as determined by reducing SDS-PAGE
- Molecular weight:24.5 kD
- Sequence:Met1-Thr190
- Formulation:Supplied as a 0.2 um filtered solution of 20mM PB, 150mM NaCl, pH 8.0. Always centrifuge tubes before opening. Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100 ug/ml. Dissolve the lyophilized protein in ddH2O. Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
- Tested applications:Bioassay
Specifications
About this item
Ubiquitin-Like-Conjugating Enzyme ATG10 (ATG10) is a ubiquitous 28kDa member of the ATG10 family protein. ATG10 acts as an E2-like enzyme, catalyzes the transfer of ATG12 to ATG5 during in the initial stages of autophagesome formation. The heterodimer of ATG5 and ATG12 subsequntly associates non-covalently with an ATG16 multimer to generate an antophagosome. ATG10 plays a role in the conjugation of ATG12 to ATG5 by interaction with MAP1LC3A. In addition, ATG10 can diretly interact with ATG5 or ATG7.
- This recombinant protein can be used for biological assays. For research use only.
Fusion-Tag: C-6 His, N-T7 tag