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Specifications
- Pk:50 µG
- Protein/peptide type:Recombinant
- Source:Cells
- Species:Human
- Tag sequence:C-Fc-6 His tag
- Storage conditions:Lyophilized protein should be stored at −20 °C, though stable at room temperature for 3 weeks. Reconstituted protein solution can be stored at 4-7 °C for 2-7 days. Aliquots of reconstituted samples are stable at −20 °C for 3 months.
- Protein synonyms:Osteoblast cadherin|OSF-4|OB-Cadherin|Cadherin-11|CDH11
- Protein/peptide name:Cadherin-11
- Purity:> 95% as determined by reducing SDS-PAGE
- Molecular weight:93.5 kD
- Sequence:Phe23-Thr617
- Formulation:Lyophilized from a 0.2 um filtered solution of PBS, pH 7.4 . Always centrifuge tubes before opening. Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100 ug/ml. Dissolve the Lyophilized protein in ddH2O. Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
- Tested applications:Bioassay
Specifications
About this item
Cadherin-11, also known as OSF-4, Osteoblast cadherin and CDH11, is a type II classical cadherin from the cadherin superfamily, integral membrane proteins that mediate calcium-dependent cell-cell adhesion. Cadherins interact with themselves in a homophilic manner in connecting cells, may thus contribute to the sorting of heterogeneous cell types. Cadherin-11 contains five cadherin domains and is mainly expressed in brain. Mature cadherin proteins consists of a large N-terminal extracellular domain, a single membrane-spanning domain, and a small, highly conserved C-terminal cytoplasmic domain. It is shown that cadherin-11 is a viable molecular target for therapeutic intervention in Glioblastoma multiforme.
- This recombinant protein can be used for biological assays. For research use only.
Fusion-Tag: C-Fc-6 His tag