Specifications
- Pk:50 µG
- Protein/peptide type:Recombinant
- Source:Cells
- Species:Human
- Tag sequence:C-6 His tag
- Storage conditions:Store at −20 °C, stable for 6 months after receipt. Please minimize freeze-thaw cycles.
- Protein synonyms:PLA2G7|LDL-Associated Phospholipase A2|PAFAH|2-Acetyl-1-Alkylglycerophosphocholine Esterase|gVIIA-PLA2|PAF 2-Acylhydrolase|1-Alkyl-2-Acetylglycerophosphocholine Esterase|Platelet-Activating Factor Acetylhydrolase|Group-VIIA Phospholipase A2|PAF Acetylhydrolase|LDL-PLA(2)
- Protein/peptide name:PAF-AH
- Purity:> 95% as determined by reducing SDS-PAGE
- Molecular weight:48.8 kD
- Sequence:Phe22-Asn441
- Formulation:Supplied as a 0.2 um filtered solution of 20mM HAc-NaCl, 150mM NaCl, 10% Glycerol, pH 4.5. Always centrifuge tubes before opening. Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100 ug/ml. Dissolve the lyophilized protein in ddH2O. Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
- Tested applications:Bioassay
Specifications
About this item
Platelet-Activating Factor Acetylhydrolase (PAFAH) is a secreted enzyme which belongs to the AB hydrolase superfamily and Lipase family and catalyzes the degradation of platelet-activating factor to biologically inactive products. PAFAH is produced by inflammatory cells and hydrolyzes oxidised phospholipids in LDL. PAFAH has been implicated in the development of atherosclerosis and has also been identified as a marker for cardiac disease. PAFAH might have a major physiologic effect in the presence of inflammatory bodily responses. PAFAH alters the action of PAF by hydrolyzing the sn-2 ester bond to yield the biologically inactive lyso-PAF. PAFAH has specificity for substrates with a short residue at the sn-2 position.
- This recombinant protein can be used for biological assays. For research use only.
Fusion-Tag: C-6 His tag