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Specifications
- Pk:50 µG
- Protein/peptide type:Recombinant
- Source:E. coli
- Species:Human
- Tag sequence:N-GST tag
- Storage conditions:Store at −20 °C, stable for 6 months after receipt. Please minimize freeze-thaw cycles.
- Protein synonyms:OL-64|Serpin A12|SERPINA12|Visceral Adipose-Specific Serpin|Vaspin|Visceral Adipose Tissue-Derived Serine Protease Inhibitor
- Protein/peptide name:Serpin A12
- Purity:> 95% as determined by reducing SDS-PAGE
- Molecular weight:71.4 kD
- Sequence:Leu21-Lys414
- Formulation:Supplied as a 0.2 um filtered solution of 50mM TrisHCl, 160mM NaCl, 0.2mM PMSF, 1mM DTT, 10% Glycerine, pH 7.2 . Always centrifuge tubes before opening. Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100 ug/ml. Dissolve the lyophilized protein in ddH2O. Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
- Tested applications:Bioassay
Specifications
About this item
Vaspin (Visceral Adipose-Specific SERPIN) is a newly described adipokine. Vaspin has three beta -sheets, nine alpha-helices, and one central loop; the structure is part of the set of distinctive features that are descriptive of Serpin family members. Vaspin is also a unique insulin sensitizing adipocytokine in obesity. A recent publication indicates that Vaspin mRNA expression in visceral fat is positively correlated with BMI and percent of body fat. and could be associated with parameters of obesity, insulin resistance, and glucose metabolism. These findings suggest a potential clinical use for Vaspin in ameliorating certain aberrations seen in the obesity metabolic syndrome.
- This recombinant protein can be used for biological assays. For research use only.
Fusion-Tag: N-GST tag