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Specifications
- Pk:100 µG
- Protein/peptide type:Recombinant
- Source:HEK293 cells
- Species:Human
- Protein synonyms:CLM-6|CMRF35-A1|CMRF-35|CD300C|CMRF35A|IGSF16
- Protein/peptide name:Igsf161
- Purity:>95% as determined by SDS-PAGE.
- Molecular weight:18.7 kDa
- Formulation:Lyophilized, PBS, pH7.4
- Tested applications:Western Blot
Specifications
About this item
CMRF35-like molecule 6 (CLM-6) is also known as CD300 antigen-like family member C, CMRF35-A1, Immunoglobulin superfamily member 16 (IgSF16) , CD antigen CD300c, which belongs to the CD300 family. CLM-6 contains one Ig-like V-type (immunoglobulin-like) domain. CD300a/c RNA and surface expression were downregulated after stimulation of plasmacytoid dendritic cells (pDCs) with TLR7 and TLR9 ligands. Exogenous interferon (IFN)-alpha down-regulated CD300a/c expression. CD300a and CD300c play an important role in the cross-regulation of TNF-alpha and IFN-alpha secretion from pDCs. CD300a and CD300c are indistinguishable on the surface of NK cells.