Human recombinant FGF Basic (from E. coli)
Catalog # PRSI40-589
Supplier: ProSci Inc.
CAS Number:
Specifications
- Pk:50 µG
- Protein/peptide type:Recombinant
- Source:E. coli
- Species:Human
- Biological activity:Assay #1: The ED50 as determined by the dose-dependent stimulation of thymidine uptake by BaF3 cells expressing FGF receptors is = 0.5 ng/mL corresponding to a specific activity of = 2 x 106 units/mg.
Assay #2: The ED50 was determined by a cell proliferation assay using balb/c 3T3 cells is = 0.1 ng/mL, corresponding to a specific activity of = 1 x 107 units/mg. - Protein synonyms:BFGF|HBGF-2|FGF-2|Basic fibroblast growth factor|Fibroblast growth factor 2|FGFB
- Protein/peptide name:FGF Basic
- Purity:>95%
- Formulation:Lyophilized
Specifications
About this item
FGF-basic is one of 23 known members of the FGF family. Proteins of this family play a central role during prenatal development and postnatal growth and regeneration of a variety of tissues, by promoting cellular proliferation and differentiation. FGF-basic is a non-glycosylated heparin binding growth factor that is expressed in the brain, pituitary, kidney, retina, bone, testis, adrenal gland liver, monocytes, epithelial cells and endothelial cells. FGF-basic signals through FGFR 1b, 1c, 2c, 3c and 4. Recombinant human FGF-basic is a 17.2 kDa protein consisting of 154 amino acid residues. Recombinant murine FGF-basic is a 16.2 kDa protein consisting of 145 amino acid residues.
- Store in working aliquots at -20°C. Avoid freeze/thaw cycles.