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Specifications
- Antigen name:Mitogen-Activated Protein Kinase Kinase 5
- Antigen symbol:MAP2K5
- Clonality:Polyclonal
- Conjugation:Unconjugated
- Host:Rabbit
- Reactivity:Human,Rat,Mouse
- Western blot:Yes
- Form:Liquid
- Antigen synonyms:PRKMK5|MEK5|MAPKK5|HsT17454
- Concentration:1 mg/mL
- Immunogen:MEK5 antibody was raised against a peptide sequence around aa. 311-315 (K-T-Y-V-G ) derived from Rat MEK5.
- Size:100 µg
- Pk:100 µG
Specifications
About this item
A family of protein kinases located upstream of the MAP kinases andresponsible for their activation has been identified. The prototype member ofthis family, designated MAP kinase kinase, or MEK-1, specifically phospho-rylates the MAP kinase regulatory threonine and tyrosine residues present inthe Thr-Glu-Tyr motif of ERK. A second MEK family member, MEK-2, resem-bles MEK-1 in its substrate specificity. MEK-3 (or MKK-3) functions to acti-vate p38 MAP kinase, and MEK-4 (also called SEK1 or MKK-4) activatesboth p38 and JNK MAP kinases. MEK-5 appears to specifically phosphory-late ERK5, whereas MEK-6 phosphorylates p38 and p38b. MEK-7 (or MKK-7)phosphorylates and activates the JNK signal transduction pathway.
Western Blot: 1:500
Antibodies were purified by affinity-chromatography using epitope-specific peptide
Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
Type:
Antigen: MAP2K5
Clonality: Polyclonal
Clone:
Conjugation: Unconjugated
Epitope:
Host: Rabbit
Isotype:
Reactivity: Human, Mouse, Rat