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- Antigen name:Hydroxysteroid 11-beta Dehydrogenase 1
- Antigen symbol:HSD11B1
- Clonality:Polyclonal
- Conjugation:Unconjugated
- ELISA:Yes
- Host:Rabbit
- Reactivity:Human,Rat,Mouse
- Western blot:Yes
- Form:Lyophilized
- Antigen synonyms:corticosteroid 11-beta-dehydrogenase isozyme 1|HSD11B1|11-beta-hydroxysteroid dehydrogenase 1|HSD11L|HDL|MGC13539|short chain dehydrogenase/reductase family 26C|OTTHUMP00000034650|hydroxysteroid (11-beta) dehydrogenase 1|SDR26C1|HSD11B|member 1|11-DH|HSD11|11-beta-HSD1
- Immunogen:A synthetic peptide corresponding a region of human HSD11B1.
- Size:50 µg
- Pk:50 µG
HSD11B1 is a microsomal enzyme that catalyzes the conversion of the stress hormone cortisol to the inactive metabolite cortisone. In addition, HSD11B1 can catalyze the reverse reaction, the conversion of cortisone to cortisol. Too much cortisol can lead to central obesity, and a particular variation in this gene has been associated with obesity and insulin resistance in children.The protein encoded by this gene is a microsomal enzyme that catalyzes the conversion of the stress hormone cortisol to the inactive metabolite cortisone. In addition, the encoded protein can catalyze the reverse reaction, the conversion of cortisone to cortisol. Too much cortisol can lead to central obesity, and a particular variation in this gene has been associated with obesity and insulin resistance in children. Two transcript variants encoding the same protein have been found for this gene.
Antibody is purified by peptide affinity chromatography method.
Antibody is lyophilized in PBS buffer with 2% sucrose. Add 50 μL of distilled water. Final antibody concentration is 1 mg/mL.
Aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
Type:
Antigen: HSD11B1
Clonality: Polyclonal
Clone:
Conjugation: Unconjugated
Epitope:
Host: Rabbit
Isotype:
Reactivity: Human, Mouse, Rat