L(+)-Histidine monohydrochloride monohydrate 98.5-101.5% (dried basis), Multi-Compendial, Macron Fine Chemicals™

: L-Histidine monohydrochloride monohydrate, (2S)-(+)-Histidine monohydrochloride monohydrate, L-Histidine hydrochloride monohydrate, (S)-(+)-Histidine monohydrochloride monohydrate, His HCl monohydrate, H-His-OH.HCl.H2O, H-His-OH·HCl·H₂O, L-3-Imidazol-4-ylalanine monohydrochloride monohydrate, L-Histidine hydrochloride hydrate

:5934-29-2

:C₆H₉N₃O₂·HCl·H₂O

:MFCD00151027

:209.63 g/mol

:259

:13,04741

:Management of Change (MOC) category = R

Environmentally Preferable:

EP/BP - Assay (C₆H₉N₃O₂·HCl) (dried basis):
98.5 - 101.0 %
EP/BP - Identification A:
Passes Test
EP/BP - Identification B:
Passes Test
EP/BP - Identification C:
Passes Test
EP/BP - Identification F:
Passes Test
EP/BP - Appearance of Solution:
Passes Test
EP/BP - pH:
3.0 - 5.0
EP/BP - Specific Rotation [Å]²º^D (+):
9.2 - 10.6 Degree
EP/BP-Ninhydrin-Positive Substances-Each:
≤ 0.2 %
EP/BP-Ninhydrin-Positive Substances-Total Impurities:
≤ 0.5 %
EP/BP - Sulfate (SO₄):
≤ 300 ppm
EP/BP - Ammonium (NH₄):
≤ 0.02 %
EP/BP - Iron (Fe):
≤ 10 ppm
EP/BP - Loss on Drying at 150°C:
7.0 - 10.0 %
EP/BP - Ash (sulfated):
≤ 0.1 %
JP - Identification:
Passes Test
JP - Optical Rotation (+):
9.2 - 10.6
JP - pH:
3.5 - 4.5
JP - Clarity and Color of Solution:
Passes Test
JP - Sulfate (SO₄):
≤ 0.028 %
JP - Ammonium (NH₄):
≤ 0.02 %
JP - Heavy Metals (as Pb):
≤ 10 ppm
JP - Iron (Fe):
≤ 10 ppm
JP - Related Substances:
Passes Test
JP - Water:
7.2 - 10.0 %
JP - Residue on Ignition:
≤ 0.10 %
JP - Assay (anhydrous basis):
99.0 - 101.0 %
Endotoxin Concentration, IU/mg ,For Information Only:
Passes Test
No Class 1,2,3 or other solvents are used or produced in the:
= 0.028 %
manufacturing or purification of the product.:
= 0.02 %
Metallic Residues: No metal catalysts or metal reagents, as defined by:
= 10 ppm
EMA Guideline EMEA/CHMP/SWP/4446/2000 , are used in the production of:
= 10 ppm
this material.:
Passes Test
Endotoxin Concentration, IU/mg:
For Information Only