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Specifications
- Pk:96
- Primary antibody reactivity:Rat
- Target protein:sL-selectin
- Description:Rat sL-Selectin ELISA Kit
- Detection range:625 - 40000 pg/ml
- Sensitivity:<20 pg/ml
Specifications
About this item
Rat sL-Selectin ELISA Kit for the quantitative measurement of rat sL-selectin.
L-selectin, also known as CD62L, is a cell adhesion molecule found on leukocytes. It belongs to the selectin family of proteins, which recognise sialylated carbohydrate groups. It is cleaved by ADAM17.SELL. L-selectin is a cell surface component that is a member of a family of adhesion/homing receptors which play important roles in leukocyte-endothelial cell interactions. The molecule is composed of multiple domains – one homologous to lectins, one to epidermal growth factor, and two to the consensus repeat units found in C3/C4 binding proteins. L-selectin acts as a "homing receptor" for leukocytes to enter secondary lymphoid tissues via high endothelial venules. Ligands present on endothelial cells will bind to leukocyte expressing L-selectin, slowing leukocyte trafficking through the blood, and facilitating entry into a secondary lymphoid organ at that point.