Fluorometric drug discovery assay kit, SIRT5, Fluor-de-Lys®

The SIRT5 Fluorometric Drug Discovery Kit is a sensitive fluorometric assay is designed to measure the lysyl desuccinylase activity of the recombinant human SIRT5.

Easy to use kit (two-step) for screening SIRT5 inhibitors/activators; includes enough active enzyme for entire plate
Suitable for high-throughput screening (Z’-factors >0,73)
Optimal, specific SIRT5 substrate means low enzyme concentration, making ‘hit’ validation easy

The SIRT5 Fluorometric Drug Discovery Kit contains an AMC (‘blue’) fluorophore that uses commonly-used wavelengths.

: Kit contains SIRT5 (Sirtuin 5) (human, rec.), FLUOR DE LYS®-Succinyl, desuccinylase substrate, FLUOR DE LYS® Developer Concentrate (20X), NAD+ (Sirtuin Substrate), Nicotinamide (Sirtuin Inhibitor), Suramin sodium (Sirtuin Inhibitor), FLUOR DE LYS® Desuccinylated Standard, Sirtuin Assay Buffer, and half volume 96-well black NBS™ microplate.

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