Thrombin is used throughout the diagnostics industry in a variety of coagulation assays, clotting factor tests and defibrination of blood or plasma for serum controls. It is also used for site specific cleavage of recombinant fusion proteins, and in biochemical and medical research applications. It is manufactured from New Zealand-sourced bovine plasma using prothrombin activated with thromboplastin extracted from bovine lung tissue.

• Plasma and blood proteins
• Off-white solid format
• Specific activity is about 90 to 300 µ/mg protein

Low specific activity thrombin has 90 to 500 NIH units/mg and greater than 50% total protein. Thrombin has been used in a study to assess persistent hypocoagulability in patients with septic shock.