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Specifications
- Antibody type:Primary
- Antigen name:B-cell lymphoma 2
- Antigen symbol:BCL2
- Clonality:Monoclonal
- Clone:83-8B
- Conjugation:Unconjugated
- Flow cytometry:Yes
- Host:Mouse
- Isotype:IgG1
- Reactivity:Drosophila,Human,Rat,Mouse
- Western blot:Yes
- Seq:02
- Form:Liquid
- Antigen synonyms:PPP1R50|Bcl-2
- Storage buffer:PBS, pH 7,2, containing 50% glycerol.
- Storage temperature:–20 °C
- Shipping temperature:Shipped on blue ice
- Immunogen:Recombinant rat Bcl-2 beta
- Purification:Purified by Protein A affinity chromatography
- Pk:100 µG
Specifications
About this item
The Bcl-2 family of proteins regulate the intrinsic apoptotic pathway and are characterized by the sharing of at least one of four conserved Bcl-2 Homology (BH) domains.
- Dilution Range: 10 µg/ml for Flow Cytometry, 1 µg/ml, ECL for Western blot
- Detects a band of ~26kDa by Western blot
Bcl-2 family members function as either pro- or anti-apoptotic factors, and are generally categorized into three groups based on structural homology and function. Bcl-2-like proteins (Bcl-2, Bcl-xL, Bcl-w, A1, and Mcl-1) are pro-survival. Pro-apoptotic members can be sub-divided into two groups: the multi-BH domain group, including Bax, Bak, and Bok; and the more numerous and diverse BH3-only group, which includes Bim, Bad, and Bid.
Type: Primary
Antigen: B-cell lymphoma 2
Clonality: Monoclonal
Clone: 83-8B
Conjugation:
Epitope:
Host: Mouse
Isotype: IgG1
Reactivity: Drosophila, Human, Mouse, Rat