About this item
The Neurotransmitter Transporter Uptake Assay Kit provides a fast, simple and reliable fluorescence-based assay for the detection of dopamine, norepinephrine and serotonin transporter (SERT, NET and DAT, respectively) activity in expressing cells.
- Homogeneous, live-cell fluorescent assay replaces radioactive assays, reducing disposal costs and eliminating associated safety risks
- One-step, homogeneous assay format is amenable to automation and high-throughput screening
- Two assay setup options offer greater flexibility, with endpoint mode for high-throughput applications, or real-time kinetic mode for mechanistic studies
Neurotransmitter transporters play a key role in depression and neurodegenerative diseases (NDD) such as Alzheimer's and Parkinson's. The ability to monitor serotonin, norepinephrine and dopamine neurotransmitter uptake is key to a better understanding of these diseases.
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