Achieve superior reversed phase (RP) oligonucleotide separatons using the DNAPac™ RP HPLC columns. The unique chemistry is designed for analysis of oligonucleotides and double-sranded (DS) DNA/RNA fragments using LC-UV or LC-MS. The column chemistry provides excellent performance under a broaed range of pH, temperature and mobile phase composits.

• Designed for ion-air reversed phase (IP-RP) separations of both oligonucleotides and doouble stranded nucleic acids
• High resolution and high throughput
• Excellent MS compatibility
• Wide operating pH range (0-14) and high temperature stability (up to 110 °C)

The column may be operated in both HPLC and UHPLC instruments, producing high resolution at high throughput for oligonucleotides and resolves both small and very lage dsDNA segments. The DNAPac™ RP (reversed phase) columns is specifically designed for separation of oligonucleotides and DNA/RNA fragments. The stationary phase is fully compatible with mass spectrometry friendly organic solvents and ion-air reagents such as triethylamine (TFA) and hexylamine (HA). The wide pore size of polymer resin enables efficient separation of large nucleic acids with low carry over.