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Specifications
- Antibody type:Primary
- Antigen name:AF4/FMR2 Family Member 2
- Antigen symbol:AFF2
- Clonality:Polyclonal
- Conjugation:Unconjugated
- Host:Rabbit
- ImmunoChemistry:Yes
- Isotype:IgG
- Reactivity:Human,Rat,Mouse
- Western blot:Yes
- Form:liquid
- Antigen synonyms:AFF2|fragile X mental retardation 2|FRAXE|FMR2|MRX2|member 2|OX19|mild or borderline mental retardation|Protein Ox19.|fragile X mental retardation gene associated with FRAXE|Fragile X mental retardation 2 protein|AFF2_HUMAN|FMR2P|AF4/FMR2 family member 2|Protein FMR-2|AF4/FMR2 family|Fragile X E mental retardation syndrome protein
- Storage buffer:Aqueous buffered solution containing 100ug/ml BSA, 50% glycerol and 0,09% sodium azide. Store at -20°C for 12 months.
- Concentration:1 ug/ul
- Shipping temperature:4 °C
- Purification:Purified by Protein A.
- Size:100 μg
- Pk:100 µl
Specifications
About this item
FMR2 is a 1311 amino acid nuclear protein belonging to the AF4 family. Expressed in the brain, placenta and lung, FMR2 exists as two isoforms produced by alternative splicing. Defects in the gene that encodes FMR2 have been found to be a cause of FRAXE, an X-linked form of mental retardation. Individuals expressing the FRAXE site also have more than two-hundred copies of a GCC repeat adjacent to CpG island, compared to six to thirty-five copies of the GCC repeat in a normal individual. It is believed that loss of FMR2 expression causes this GCC expansion of the FRAXE site.
WB(1:100-1000), IHC-P(1:100-500), IF(IHC-P)(1:50-200)
Type: Primary
Antigen: AFF2
Clonality: Polyclonal
Clone:
Conjugation: Unconjugated
Epitope:
Host: Rabbit
Isotype: IgG
Reactivity: Human, Mouse, Rat