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Specifications
- Antibody type:Primary
- Antigen name:Neurotrophin 4/5
- Clonality:Polyclonal
- Conjugation:Unconjugated
- ELISA:Yes
- Host:Chicken
- Isotype:IgY
- Reactivity:Human,Mouse
- Epitope:Human NT4/5 peptides, amino acids 104-118 and 198-210
- Cross adsorption:No
- Format:Liquid
- Antigen synonyms:NTF5|NTF4,
- Immunogen:Mixture of two human NT4/NT5 peptides (104-118 and 198-210 aa).
- Size:500 µl
- Pk:500 µl
Specifications
About this item
NT4 is a member of the neurotrophin family, in knockout animals NT4 deficient mice appeared little changed from wildtype animals, however NT4 is a powerful neurotrophic factor for periferial neuronal ganglia and is capable if sustaining ganglia neurons in vitro. NT4 is closely related to both NGF and BDNF. FUNCTION: Target-derived survival factor for peripheral sensory sympathetic neurons. SUBCELLULAR LOCATION: Secreted protein. TISSUE SPECIFICITY: Highest levels in prostate, lower levels in thymus, placenta, and skeletal muscle. Expressed in embryonic and adult tissues. SIMILARITY: Belongs to the NGF-beta family.
The antibody reacts with human and mouse NT-4//5 proteins and likely with other species based upon homology. The antibody has not been tested in IHC or western blot
Application Information:
ELISA at suggested dilution of 1:500-1:2,000. Biosensis recommends that the optimal working dilution should be determined by the end user.
Type: Primary
Antigen: Neurotrophin-4/5; NT4/NT5
Clonality: Polyclonal
Clone:
Conjugation: Unconjugated
Epitope: Human NT4/5 peptides, amino acids 104-118 and 198-210
Host: Chicken
Isotype: IgY
Reactivity: Human, Mouse