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573 results for Cellular Assays

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Cellular Assays

Cellular assays have always been a powerful tool in the research lab. They are incredibly versatile, and can be designed to measure virtually any cellular or biochemical function. Sensitive detection of fluorescent probes aid in evaluating cell signalling and death pathways, which is useful for the rapid quantification of cell viability. Cellular assays can be used to measure the effects of different treatments on cell viability and to evaluate toxic effects mediated through a variety of mechanisms.

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DNMT colorimetric drug discovery tests

DNMT colorimetric drug discovery tests

Supplier: Enzo Life Sciences

DNMT colorimetric drug discovery kit is a simple method to detect DNA methylation activity or inhibition.

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Cell Meter™ Cellular Senescence Activity Assay Kit *Green Fluorescence*

Cell Meter™ Cellular Senescence Activity Assay Kit *Green Fluorescence*

Supplier: AAT BIOQUEST

Cellular Senescence is an irreversible growth arrest triggered in order to prevent growth in DNA damaged cells.

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Maybridge Screening library

Maybridge Screening library

Supplier: THERMO SCIENTIFIC MAYBRIDGE

The Maybridge portfolio consists of high-quality hit-like, lead-like and drug-like compounds which can generate valuable data in screening programs. They are developed specifically to support the pharmaceutical drug discovery process.

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FLUOR DE LYS® HDAC fluorometric activity assay kit

Supplier: Enzo Life Sciences

The FLUOR DE LYS® HDAC fluorometric activity assay kit is a sensitive and convenient alternative to protocols utilizing radiolabeled, acetylated histones or peptide/HPLC methods for the assay of histone deacetylases. It is based on the unique FLUOR DE LYS® (Fluorimetric Histone deAcetylaseLysyl) substrate and developer combination and provides an assay that can be carried out in two simple mixing steps, all on the same 96-well plate. Histone deacetylase inhibitors have shown promise as anti-tumor agents and naturally this has stimulated interest in the screening of compounds for HDAC inhibition.

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Cholesterol cell-based detection assay kit

Supplier: Cayman Chemical

Cholesterol Cell-Based Detection Assay Kit is a 192-well assay for measurement of cholesterol.

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Oct4 transcription factor assay kit

Oct4 transcription factor assay kit

Supplier: Cayman Chemical

96-Well assay for measurement of Oct4.

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CFDA SE Cell proliferation assay kit

Supplier: Biotium

Cell proliferation dyes diffuse passively into cells and covalently label intracellular proteins, resulting in long term cell labelling. They are non-fluorescent until they are hydrolysed by intracellular esterase's. The dyes then react with intracellular amines forming fluorescent conjugates that are retained in the cell. Immediately after staining, a single, bright fluorescent population will be detected by flow cytometry. With each cell division, daughter cells inherit roughly half of the fluorescent label, allowing the number of cell divisions that occur after labelling to be detected by the appearance of successively dimmer fluorescent peaks on a flow cytometry histogram compared to cells analysed immediately after staining. Staining is formaldehyde fixable.

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Cyclic-GMP fluorescent assay kits, CatchPoint™

Cyclic-GMP fluorescent assay kits, CatchPoint™

Supplier: MOLECULAR DEVICES

CatchPoint™ cGMP Fluorescent Assay Kits measure cGMP levels via a competitive immunoassay format. The second messenger cyclic GMP (cGMP) modulates cellular processes, including smooth muscle relaxation, kidney function, and inflammation, by activating effectors such as protein kinases, cGMP-dependent phosphodiesterases, and cGMP-gated ion channels.

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Acetyltransferase activity kit

Supplier: Enzo Life Sciences

For the measurement of acetyl-CoA dependent acetyltransferase activity in purified in vitro samples that do not contain reductants from any species.

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Fluor-de-Lys® SIRT1 fluorometric drug discovery assay kit

Supplier: Enzo Life Sciences

A Fluor-de-Lys® fluorescent assay system. The SIRT1 Fluorescent Activity Assay/Drug Discovery Kit is a complete assay system designed to measure the lysyl deacetylase activity of the recombinant human SIRT1 included in the kit.

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Fluor-de-Lys® SIRT2 fluorometric drug discovery assay kit

Supplier: Enzo Life Sciences

A Fluor-de-Lys® fluorescent assay system. The SIRT2 Fluorescent Activity Assay/Drug Discovery Kit is a complete assay system designed to measure the lysyl deacetylase activity of the recombinant human SIRT2 included in the kit. The kit is ideal for chemical library screening for candidate inhibitors or activators or kinetic assay of the enzyme under varying conditions.

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ROS-ID™ total ROS detection kit

ROS-ID™ total ROS detection kit

Supplier: Enzo Life Sciences

This kit is designed to directly monitor real time reactive oxygen and/or nitrogen species (ROS/RNS) production in live cells using fluorescence microscopy and/or flow cytometry.

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Nitric oxide reagents and kits

Nitric oxide reagents and kits

Supplier: Biotium

Nitric oxide donors, nitric oxide synthase inhibitors and nitric oxide detection reagents and kits for nitric oxide (NO) studies.

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RedDot™1 Far-Red Nuclear Stain, 200X in Water, Biotium

RedDot™1 Far-Red Nuclear Stain, 200X in Water, Biotium

Supplier: Biotium

RedDot™1 is a far-red cell membrane-permeable nuclear dye similar to Draq5™. The dye is ideal for specifically staining the nuclei of live cells.

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CF® Dye Dextran 3500 MW, anionic and fixable

Supplier: Biotium

CF® dye labeled dextrans could be used as a fluorescent fluid-phase markers to study cell permeability, endocytosis, or mechanisms of biomolecular delivery. The dextran is 3,500 MW, and contains a formaldehyde-fixable free-amine group.

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NUCLEOLAR-ID® Green detection kit

Supplier: Enzo Life Sciences

Specifically designed for visualizing microscopically nucleoli in living cells.

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Hydrogen peroxide fluorometric detection kit

Supplier: Enzo Life Sciences

The Hydrogen Peroxide Fluorometric Detection Kit provides fast results in just 10 minutes for the measurement of either hydrogen peroxide or peroxidase activity in a convenient one-step homogeneous assay.

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Red long-term cell tracer, CYTO-ID®

Supplier: Enzo Life Sciences

CYTO-ID® is a live cell fluorescent labelling used for a long term cell viability, cytotoxicity, cell adhesion, cell migration, and cell-cell fusion studies.

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Live-dead cell staining kit

Supplier: Enzo Life Sciences

Kit utilises Live-dye™, a cell permeable green fluorescent dye (Ex(max): 488 nm; Em(max): 518 nm), to stain live cells. Dead cells can be easily stained by propidium iodide (PI), a red fluorescent dye (Ex(max): 488 nm; Em(max): 615 nm), which in viable cells is actively pumped out of the cytoplasm.

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Uric acid assay kit

Uric acid assay kit

Supplier: Cayman Chemical

Uric Acid Assay Kit is used to measure uric acid in serum, plasma and urine.

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Caspase-3 assay kits, NucView™ 488

Caspase-3 assay kits, NucView™ 488

Supplier: Biotium

NucView® 488 caspase-3 substrate is a novel cell membrane-permeable fluorogenic caspase substrate designed for detecting caspase-3 activity within live cells in real time.

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Cell proliferation assay kit, WST-1

Supplier: Cayman Chemical

WST-1 Proliferation Assay Kit provides an easy to use tool for studying the induction and inhibition of cell proliferation in any in vitro model. The assay is based on the reduction of tetrazolium salt WST-1 to soluble formazan by electron transport across the plasma membrane of dividing cells. This kit will also allow investigators to screen drug candidates involved in regulation of cell cycle.

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Cell Meter™ Cellular Senescence Activity Assay Kit *Red Fluorescence*

Cell Meter™ Cellular Senescence Activity Assay Kit *Red Fluorescence*

Supplier: AAT BIOQUEST

Cellular Senescence is an irreversible growth arrest triggered in order to prevent growth in DNA damaged cells.

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LEADING LIGHT® Wnt Reporter Assay Starter Kit

Supplier: Enzo Life Sciences

The LEADING LIGHT® Wnt Reporter Assay Starter Kit is a cell-based luciferase activity test suitable for 96 well plate format.

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CV-Cathepsin B detection kit

Supplier: Enzo Life Sciences

Based on the dye cresyl violet and the cathepsin B ArgArg peptide recognition sequence, this kit allows the detection of cathepsin B activity in living cells by fluorescence microscopy.

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FLUOR DE LYS® HDAC1 fluorometric drug discovery assay kit

Supplier: Enzo Life Sciences

The HDAC1 Fluorescent Activity Assay/Drug Discovery Kit is a complete assay system designed to measure the lysyl deacetylase activity of the recombinant human HDAC1 included in the kit.

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FLUOR DE LYS® SIRT3 fluorometric drug discovery assay kit

Supplier: Enzo Life Sciences

A Fluor-de-Lys® fluorescent assay system. The SIRT3 Fluorescent Activity Assay/Drug Discovery Kit is a complete assay system designed to measure the lysyl deacetylase activity of the recombinant human SIRT3 included in the kit. The kit is ideal for chemical library screening for candidate inhibitors or activators or kinetic assay of the enzyme under varying conditions.

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Glutathione Cell-Based Detection Kit (Blue Fluorescence)

Glutathione Cell-Based Detection Kit (Blue Fluorescence)

Supplier: Cayman Chemical

For rapid and easy determination of GSH in whole cells.

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LEADING LIGHT® Wnt reporter cell line

Supplier: Enzo Life Sciences

Wnt reporter cell line for discovering Wnt pathway modulators.

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Red IHC chromogen (AP), HIGHDEF®

Supplier: Enzo Life Sciences

Red IHC chromogen (AP) is intended to be used in conjunction with alkaline phosphatase (AP)-based immunostaining or in situ hybridisation systems.

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