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Piericidin A

Supplier: Apollo Scientific

Piericidin A

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Piericidin A (from Streptomyces sp. MST-AS5364) ≥95% (by HPLC)

Supplier: ENZO LIFE SCIENCES

Antibiotic. Specific and potent inhibitor of NADH-ubiquinone oxidoreductase (complex I) that binds to ubiquinone binding site(s). Inhibits both mitochondrial and bacterial NADH ubiquinone oxidoreductase. Anticancer agent that prevents up-regulation of GRP78, and exhibits cytotoxic activity for etoposide resistant cancer cells under glucose-deprived conditions.

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