You searched for: Bafilamycin A1

Supplier: Apollo Scientific

Bafilamycin A1

Supplier: Thermo Fisher Scientific

Bafilamycin A1 95%

Supplier: ENZO LIFE SCIENCES

Macrolide antibiotic that acts as a potent and selective inhibitor of vacuolar-type H⁺-ATPase (V-type) (IC₅₀=004 - 0.4 nmol/mg). Valuable tool for distinguishing among different types of ATPases. Inhibitor of endosomal acidification. Blocks lysosomal cholesterol trafficking in macrophages. Blocks pH regulation in brain cells.

Supplier: Thermo Fisher Scientific

Bafilomycin A1 is a specific potent inhibitor of vacuolar ATPases. Used as an antibacterial, antifungal, antineoplastic, an immunosuppressive and also prevents maturation of autophagic vacuoles by inhibiting fusion between autophagosomes and lysosomes and is a macrolide antibiotic and potent and selective inhibitor of vacuolar-type H+ ATPase (V-ATPase).