Ensuring your success with LC-MS

Accelerate your LC-MS method development with our complete portfolio of columns, solvents and sample prep products that are designed to simplify your analysis while improving precision.

Avantor solutions are engineered to help you reduce variability, enhance sensitivity and maintain reproducibility so you can focus on your analysis, not your setup. When you partner with Avantor, you can expect:

• Shorter setup times
• Lower detection limits
• Cleaner spectra and quantitation
• Proven compatibility across products
• Support from LC-MS specialists

Boost sensitivity. Reduce background. Save time.

High-purity solvents can make or break your analysis. Avantor offers a full range of LC-MS solvents that have been engineered to meet the demands of today's sensitive instruments. Mobile phases that drive baseline stability and sensitivity can help provide lower detection limits, more reliable quantitation, cleaner spectra and better instrument performance, while reducing noise and variability.

That’s why Avantor offers HPLC, UHPLC and LC-MS grades — including HiPerSolv CHROMANORM^® and J.T.Baker^® LC-MS and Ultra LC-MS solvents — along with ready to use pre blends with formic acid or TFA to minimize contamination and speed setup.

Whether you're optimizing detection limits, troubleshooting signal suppression or running high-throughput assays, you can find the performance you need from brands you trust.

Choose columns made for precision and built to last.

Find your ideal column for small molecule analysis, from rugged general-purpose C18 to specialty HILIC and shape-selective phases. Avantor ACE columns offer industry-leading reproducibility and are built on ultra-inert silica for excellent peak shape and batch-to-batch consistency.

Why Avantor ACE^® columns

• Available in a wide range of selectivities
• Broad pH stability (≈1.5–11.5)
• Suitable for discovery, QC and method transfer
• Also available: Vydac^®, Alltima^®, Prevail™ and Genesis™ produced to original specifications

Protect Your Investment. Improve Recovery.

Effective sample prep helps safeguard your columns and improve your data quality. With J.T.Baker BAKERBOND^® chemistries, you get high-recovery, low-variance solid phase extraction (SPE) solutions that are engineered to meet your throughput and cleanliness needs.

Speed up development. Improve selectivity.

Accelerate your method development process with curated Avantor ACE Method Development Kits (MDKs). Each kit is built to help you screen orthogonal chemistries quickly and optionally includes ChromSword™ software for systematic optimization.