Avantor® Hichrom RPB is a high purity base deactivated silica which offers a unique selectivity due to the proprietary C8/C18 multi-alkyl bonding and exhaustive endcapping employed. The range includes 3.5, 5 and 10 μm phases, which are suitable for LC-MS applications and preparative separations respectively.

• Increased productivity due to reduced analysis time
• Decreased column length without sacrificing efficiency
• Excellent chromatography

Avantor® Hichrom RPB is specifically designed for the reversed-phase separation of basic molecules. Residual acidic sites have been eliminated whilst monolayer coverage of the high purity silica surface has been retained to obtain optimum plate efficiency. Both octyl- and octadecylsilanes are bonded to give a material which combines the robustness of a C18 phase with the high coverage of a C8 phase. Excellent peak shapes are obtained for basic drug molecules. In addition, acids and bases can be similarly chromatographed under suitably buffered conditions.

* Use with freestanding holder HI-161 and column coupler HI-081.