The selectivity offered by ZIC®-HILIC (Hydrophilic Interaction Liquid Chromatography) is suitable for a wide variety of molecules containing hydrophilic or ionisable functional groups.

• Straightforward separation of polar and hydrophilic compounds
• Orthogonal selectivity compared to reversed-phase
• High-density bonded sulfobetaine zwitterionic stationary phase
• Low cost per analysis due to robust stationary phase

This includes compounds such as carbohydrates, metabolites, acids and bases, organic and inorganic ions, metal complexes, amino acids, peptides, protein digests, plant and cell extracts, plus much more. These compounds are normally characterised by a small or negative LogP (Octanol-water partition coefficient) value and have poor retention on reversed-phase columns.