The level of volatile organic solvents in pharmaceutical raw materials or finished product is defined and monitored. Residual solvents are classified according to their risk assessment classes. A selection of residual solvent standards is now available from Avantor.

Residual Solvents Class 1 acc to Ph Eur Ver 8.8: 5 components; benzene 4 mg/ml; 1,2-dichloroethane 10 mg/ml ; tetrachloromethane 8 mg/ml; 1,1-dichloroethene 16 mg/ml; 1,1,1-trichloroethane 20 mg/ml in imethylsulphoxide

Residual Solvents Class 1 acc. to Ph Eur Ver 10: 5 components; benzene 2 mg/L; tetrachloromethane (carbon tetrachloride) 4 mg/L; 1,2-dichloroethane 5 mg/L; 1,1-dichloroethene 8 mg/L; 1,1,1-trichloroethane 1500 mg/L in dimethyl sulphoxide.