650 Results for: "Shenandoah Biotechnology"

Supplier: Shenandoah Biotechnology

Procalcitonin is a precursor of the peptide hormone calcitonin. Procalcitonin is mainly produced by the neuroendocrine cells of the lung and thyroid gland, but may be secreted ubiquitously during inflammation or infection. 1 * 2 µG

Supplier: Shenandoah Biotechnology

Interleukin 3 is a cytokine that is produced by activated T cells and mast cells. IL-3 induces the differentiation of hematopoietic stem cells into myeloid precursor cells, such as erythrocyte, megakaryocyte, granulocyte, monocyte, and dendritic cell 1 * 2 µG

Supplier: Shenandoah Biotechnology

CD40 Ligand (CD40L), or CD154, is a membrane glycoprotein and differentiation antigen that is expressed on the surface of T cells, m onocytes, basophils, eosinophils, platelets, dendritic cells, and endothelial cells. 1 * 100 µG

Supplier: Shenandoah Biotechnology

Interleukin 15 (IL-15) is a widely expressed proinflammatory cytokine that is structurally and functionally related to interleukin 2 (IL-2). IL-15 signals through JAK kinases to activate STAT3, STAT5, and STAT6 transcription factors. 1 * 500 µG

Supplier: Shenandoah Biotechnology

Macrophage colony stimulating factor (M-CSF) is a hematopoietic growth factor that is widely produced by a variety of cells. M-CSF stimulates the proliferation and differentiation of hematopoietic stem cells into monocyte and macrophage cell types. 1 * 2 µG

Supplier: Shenandoah Biotechnology

Interleukin 15 (IL-15) is a widely expressed proinflammatory cytokine that is structurally and functionally related to interleukin 2 (IL-2). IL-15 signals through JAK kinases to activate STAT3, STAT5, and STAT6 transcription factors. 1 * 10 µG

Supplier: Shenandoah Biotechnology

Macrophage inflammatory protein-1 beta (MIP-1-beta), also known as CCL4, is produced by macrophages and functions as a mitogen-indu cible cytokine. MIP-1-beta signals through the chemokine receptor CCR5 to chemoattract immune cells. 1 * 2 µG

Supplier: Shenandoah Biotechnology

Interleukin 10 (IL-10) is an anti-inflammatory cytokine produced by macrophages and type 2 T helper (Th2) cells. IL-10 inhibits the production of pro-inflammatory cytokines. 1 * 2 µG

Supplier: Shenandoah Biotechnology

Interleukin 22 (IL-22), also called IL-TIF, is an IL-10 family member that is produced by activated dendritic cells and T lymphocyte s. IL-22 signals via a heteroduplex receptor consisting of IL-22R and IL-10Rbeta chains. 1 * 2 µG

Supplier: Shenandoah Biotechnology

Activin A is a member of the transforming growth factor beta (TGF-β) family of proteins and functions to stimulate follicle-stimulat ing hormone (FSH) secretion. Activins are produced in many tissue types including the skin, gonads, lungs, and pitui 1 * 2 µG

Supplier: Shenandoah Biotechnology

Stem cell factor (SCF) is a cytokine made by fibroblasts and endothelial cells. SCF binds to the receptor c-Kit/CD117 and plays a c ritical role in the maintenance, survival, and differentiation of hematopoietic stem cells. 1 * 2 µG

Supplier: Shenandoah Biotechnology

Interleukin 6 (IL-6) is a cytokine that is expressed by T cells, macrophages, and muscle cells. IL-6 acts to stimulate an immune re sponse upon infection or trauma. IL-6 has both pro-inflammatory and anti-inflammatory functions. 1 * 2 µG

Supplier: Shenandoah Biotechnology

Granulocyte-colony stimulating factor (G-CSF) is a cytokine that functions as a potent inducer of neutrophilic granulocyte prolifera tion, terminal differentiation, and activation. 1 * 2 µG

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ANIMAL-FREE MOUSE IL-6 1 * 2 µG

Supplier: Shenandoah Biotechnology

Interleukin 1 beta (IL-1β) is a pro-inflammatory cytokine that is produced by monocytes, macrophages, and dendritic cells (DCs). IL -1β signals through the IL-1 receptor, type 1 (IL-1R1) to activate the myeloid differentiation primary response 88 (MY 1 * 2 µG

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Interleukin 17E (IL-17E), also known as IL-25, is a member of the IL-17 family of cytokines. IL-17E binds to the IL-17BR receptor t o stimulate the secretion of the proinflammatory interleukin 8 (IL-8) chemokine. 1 * 10 µG

Supplier: Shenandoah Biotechnology

Epidermal growth factor (EGF) is a growth factor that stimulates the proliferation, differentiation, and survival of epithelial and epidermal cells. 1 * 500 µG

Supplier: Shenandoah Biotechnology

Leptin is a hormone that is produced by adipose tissue and plays critical roles in the physiologic regulation of body weight. Lepti n acts through the leptin receptor (LEPR) to regulate adipose mass by inhibiting hunger and balancing energy usage. 1 * 10 µG

Supplier: Shenandoah Biotechnology

Brain-derived neurotrophic factor (BDNF) is a nerve growth factor that binds two receptors, the low-affinity nerve growth factor rec eptor (LNGFR) and the tropomyosin receptor kinase B (TrkB), to support neuron growth and survival. 1 * 2 µG

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Insulin-like growth factor I (IGF-I) is a growth factor that is produced by the liver. IGF-1 production is stimulated by growth hor mone (GH). IGF-I binds the insulin-like growth factor 1 receptor (IGF1R) and the insulin receptor. 1 * 1 mg

Supplier: Shenandoah Biotechnology

Oncostatin M (OSM) is a cytokine that is produced by macrophages, dendritic cells, and T lymphocytes during inflammatory events. Th e Type-I and Type-II OSM receptors are located on the cell surface of endothelial and tumor cells. 1 * 2 µG

Supplier: Shenandoah Biotechnology

Platelet-derived growth factor (PDGF) is an important regulator of cell growth, proliferation, and angiogenesis. PDGF synthesis is induced by IL-1, IL-6, TNF-a, TGF-b and EGF signaling. 1 * 2 µG

Supplier: Shenandoah Biotechnology

Interleukin 17E (IL-17E), also known as IL-25, is a member of the IL-17 family of cytokines. IL-17E binds to the IL-17BR receptor t o stimulate the secretion of the proinflammatory interleukin 8 (IL-8) chemokine. 1 * 500 µG

Supplier: Shenandoah Biotechnology

PRIME-XV IS21 Supplement (50X) is a serum-free supplement optimized for use with PRIME-XV Neural Basal Medium to support maintenance and long- term culture of neuronal cells. This supplement is supplied as a 50X concentrated solution and should be di 1 * 10 mL

Supplier: Shenandoah Biotechnology

Interleukin 16 (IL-16) is produced by CD4+ and CD8+ T cells and functions as a chemoattractant for lymphocytes, monocytes, eosinophi ls, dendritic cells, and Langerhans cells. 1 * 2 µG

Supplier: Shenandoah Biotechnology

ANIMAL-FREE MOUSE IL-7 1 * 2 µG

Supplier: Shenandoah Biotechnology

Interleukin 6 (IL-6) is a cytokine that is expressed by T cells, macrophages, and muscle cells. IL-6 acts to stimulate an immune re sponse upon infection or trauma. IL-6 has both pro-inflammatory and anti-inflammatory functions. 1 * 2 µG

Supplier: Shenandoah Biotechnology

Glial cell-derived neurotrophic factor (GDNF) is a neurotrophic factor that signals through a multicomponent receptor system to acti vate receptor tyrosine kinase RET signaling. 1 * 2 µG

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Myostatin (GDF-8), a conserved member of the TGF-beta superfamily, is an essential regulator of skeletal muscle mass and cardiac mus cle development and function. Myostatin is a secreted protein that negatively regulates skeletal muscle growth. 1 * 2 µG

Supplier: Shenandoah Biotechnology

Interleukin 9 (IL-9) is a cytokine produced by type 2 T helper (Th2) cells and regulates hematopoietic cells. IL-9 signals through the interleukin 9 receptor (IL9R) to activate STAT signaling. 1 * 2 µG