33224 Results for: "Eosin+Y&pageNo=68"

Supplier: Abcam

Rabbit monoclonal [EPR18741-67] to Albumin - BSA and Azide free (Detector).

Supplier: Abcam

Rabbit monoclonal [EPR24151-69] to GNAO1 - BSA and Azide free.

Supplier: Abcam

Rabbit monoclonal [EPR23668-64] to IMPA2 - BSA and Azide free.

Supplier: Abcam

Rabbit monoclonal [28-8] to PD-L1 - BSA and Azide free.

Supplier: Abcam

Rabbit monoclonal [EPR13144-62] to UAP56 - BSA and Azide free.

Supplier: Abcam

Rabbit monoclonal [EPR10932-62] to Cytokeratin 9 - BSA and Azide free.

Supplier: Abcam

Rabbit monoclonal [EPR14330-67] to TMEM192 - BSA and Azide free.

Supplier: Abcam

Rabbit monoclonal [EPR23884-69] to LAG-3 - BSA and Azide free (Detector).

Supplier: Abcam

Rabbit monoclonal [EPR20512-28] to GSDMD - BSA and Azide free (Capture).

Supplier: Abcam

Rabbit monoclonal [EPR19762-66] to IGFBP4 - BSA and Azide free (Detector).

Supplier: Abcam

Rabbit monoclonal [EPR23757-38] to PCGF1 - BSA and Azide free.

Supplier: Apollo Scientific

3-(4-Chloro-2-fluorophenyl)-1-oxa-3,8-diazaspiro[4.5]decan-2-one

Supplier: Apollo Scientific

2-(7-Oxo-5,8-diazaspiro[3.4]oct-6-yl)benzoic acid

Supplier: Bioss

HERC6.

Supplier: Bioss

The protein encoded by this gene shares significant homology to the adenomatous polyposis coli (APC) protein-binding EB1 gene family. This protein is a microtubule-associated protein that is necessary for spindle symmetry during mitosis. It is thought to play a role in the tumorigenesis of colorectal cancers and the proliferative control of normal cells. Alternative splicing of this gene results in multiple transcript variants.

Supplier: Apollo Scientific

1H,1H,8H,8H-Dodecafluoro-1,8-octandiol 98%

Supplier: Bioss

The ADP-ribosylation factor (Arf) family comprises a group of structurally and functionally conserved 21 kDa proteins, which are members of the Ras superfamily of regulatory GTP-binding proteins. Arf is involved in intracellular protein traffic to and within the Golgi complex. Arf has a number of disparate activities including maintenance of organelle integrity, assembly of coat proteins, as a co-factor for cholera toxin and as an activator of phospholipase D. Like other small GTPases, Arf is found to be active when bound to GTP and inactive when bound to GDP. Arf's activation is dependent upon guanine nucleotide exchange factors (GEFs) which increase the rate of exchange of bound GDP with GTP. All GEFs have a highly conserved Sec7 domain. GEF activity lies in the Sec7 domain and this activity has been shown to be inhibited by the fungal metabolite brefeldin-A (BFA). A small group of GEFs which are insensitive to brefeldin-A (BFA) include cytohesin-1 (B2-1), cytohesin-2 (ARNO), cytohesin-3 (ARNO3), and cytohesin-4. All cytohesins function in the cell periphery and contain a pleckstrin homology (PH) domain. The PH domain has been shown to interact with phosphatidylinositol 3,4,5-triphosphate and is believed to promote membrane targeting of the cytohesins. Recruitment of the cytohesins to the membranes can occur in response to tyrosine kinase receptor activation. This response appears to require the activation of phosphatidylinositol 3-kinase (PI 3-kinase).

Supplier: Bioss

Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems. The G(o) protein function is not clear. Stimulated by RGS14.

Supplier: Bioss

Transcription factor that controls transcriptional expression of its target genes by binding to the E box (5'-CANNTG-3'). Plays a role at early stages of development of specific neural lineages in most regions of the CNS, and of several lineages in the PNS. Acts synergistically with FOXN4 to specify the identity of V2b neurons rather than V2a from bipotential p2 progenitors during spinal cord neurogenesis, probably through DLL4-NOTCH signaling activation. Essential for the generation of olfactory and autonomic neurons (By similarity).

Supplier: Bioss

ADCK4, AarF domain containing kinase 5, is a member of group i collagen (fibrillar forming collagen). The function of this protein is not yet clear. It is not known if it has protein kinase activity and what type of substrate it would phosphorylate (Ser, Thr or Tyr). There are 2 named isoforms produced by alternative splicing.

Supplier: Bioss

GLCCI1, also known as TSSN1, GIG18 or FAM117C, is a 547 amino acid protein found in thymus and CD4(+)CD8(+) cells during specific stages of spermatogenesis in testis. Subject to phosphorylation, GLCCI1 is encoded by a gene located on human chromosome 7, which houses over 1,000 genes and comprises nearly 5% of the human genome. Chromosome 7 has been linked to Osteogenesis imperfecta, Pendred syndrome, Lissencephaly, Citrullinemia and Shwachman-Diamond syndrome. The deletion of a portion of the q arm of chromosome 7 is associated with Williams-Beuren syndrome, a condition characterised by mild mental retardation, an unusual comfort and friendliness with strangers and an elfin appearance. Deletions of portions of the q arm of chromosome 7 are also seen in a number of myeloid disorders including cases of acute myelogenous leukemia and myelodysplasia.

Supplier: Bioss

Primary canalicular bile undergoes a process of fluidization and alkalinization along the biliary tract that is influenced by several factors, including hormones, innervation/neuropeptides and biliary constituents. The excretion of bicarbonate at both the canaliculi and the bile ducts is an important contributor to the generation of bile-salt independent flow. Bicarbonate is secreted from hepatocytes and cholangiocytes through parallel mechanisms, which involve chloride efflux through activation of chloride channels and further bicarbonate secretion via AE2 (also designated SLC4A2)-mediated chloride/bicarbonate exchange. The AE2 protein regulates pH, chloride concentration, cell volume and transepithelial ion transport in many tissues. Gene silencing of AE2 causes a marked inhibition of unstimulated and secretin-stimulated chloride/bicarbonate exchange, which maintains the bile acid pool that is crucial for secretin to induce bicarbonate-rich choleresis.

Supplier: Bioss

Receptor for TNFSF13/APRIL and TNFSF13B/TALL1/BAFF/BLYS that binds both ligands with similar high affinity. Mediates calcineurin-dependent activation of NF-AT, as well as activation of NF-kappa-B and AP-1. Involved in the stimulation of B- and T-cell function and the regulation of humoral immunity (By similarity).

Supplier: Bioss

Putative O-methyltransferase.

Supplier: Bioss

GALR1 is a G-protein-coupled receptor for the neuropeptide galanin that influences endocrine secretions, intestinal motility, memory, weight, and pain perception. GALR1 inhibits adenylyl cyclase via a G protein of the Gi/Go family. GALR1 is widely expressed in the brain and spinal cord, and in peripheral sites such as the small intestine and heart. The rat galanin receptor cDNA cloned from an insulinoma cell line is a predicted 346-amino acid G protein-coupled receptor with 92% homology to the human GALR1.

Supplier: Bioss

C3orf37, also known as DC12 or MGC111075, is a 354 amino acid protein encoded by a gene that maps to human chromosome 3q21.3. Chromosome 3 is made up of approximately 214 million bases encoding over 1100 genes. Notably, there is a chemokine receptor gene cluster and a variety of human cancer related loci on chromosome 3. Particular regions of the chromosome 3 short arm are deleted in many types of cancer cells. Key tumour suppressing genes on chromosome 3 encode apoptosis mediator RASSF1, cell migration regulator HYAL1 and angiogenesis suppressor SEMA3B. Marfan Syndrome, porphyria, von Hippel-Lindau syndrome, osteogenesis imperfecta and Charcot-Marie-Tooth disease are a few of the numerous genetic diseases associated with chromosome 3.

Supplier: Bioss

Natural killer (NK) cells express multiple C-type (calcium-dependent) lectin-like receptors, that interact with major histocompatibility complex class I molecules and either inhibit or activate cytotoxicity and cytokine secretion. CLEC1B (also known as CLEC-2) is a C-type lectin-like receptor expressed in myeloid cells and NK cells.

Supplier: Bioss

Abhydrolase domain containing 3 (ABHD3) belongs to the AB hydrolase superfamily. It has a central core predicted to form alpha/beta hydrolase folds and has a ser-ala-his catalytic triad characteristic of peroxidases.

Supplier: Bioss

Oxidation of 5,6-dihydroxyindole-2-carboxylic acid (DHICA) into indole-5,6-quinone-2-carboxylic acid. May regulate or influence the type of melanin synthesised.

Supplier: Bioss

The homeobox is DNA sequence that is approximately 180 base pairs long that is involved in all steps of the developmental regulation of animals, fungi and plants, from embryogenesis to cell differentiation. The homeobox encodes a protein domain of about 60 amino acids, called the homeodomain, that can bind to DNA. The gastrulation brain homeobox 1 (GBX1) gene, along with another homeobox gene (EN2), maps to chromosome 7q36, and is expressed in septal and pallidal areas and in the basal forebrain cholinergic system, an area implicated in Alzheimer's disease. The GBX1 gene encodes the GBX1 protein, which localizes to the nucleus and contains 1 homeobox DNA-binding domain.