Supplier: ProSci Inc.

Transport of folate compounds into mammalian cells can occur via receptor-mediated or carrier-mediated mechanisms. A functional coordination between these 2 mechanisms has been proposed to be the method of folate uptake in certain cell types. Methotrexate (MTX) is an antifolate chemotherapeutic agent that is actively transported by the carrier-mediated uptake system. SLC19A1 plays a role in maintaining intracellular concentrations of folate.Transport of folate compounds into mammalian cells can occur via receptor-mediated (see MIM 136430) or carrier-mediated mechanisms. A functional coordination between these 2 mechanisms has been proposed to be the method of folate uptake in certain cell types. Methotrexate (MTX) is an antifolate chemotherapeutic agent that is actively transported by the carrier-mediated uptake system. RFC1 plays a role in maintaining intracellular concentrations of folate.

Supplier: Portwest

This flame-retardant boilersuit is most suitable for use within the welding industry, with excellent protection for workers who are exposed to extreme heats. Made of Bizweld 330 fabric (100% cotton drill).

Supplier: FRISTADS KANSAS

T-shirt with short sleeves, made of 44,5% polyester Cocona® and 55,5% standard polyester. The material transports moisture, absorbs odour, dries very quickly and offers UV protection.

Supplier: FRISTADS KANSAS

Cold resistant jacket made from Airtech® fabric (100% polyamid), a water and windproof, breathable material. The jacket features quilted lining. Exposed areas are reinforced with nylon.

Supplier: FRISTADS KANSAS

Heavy men's piqué poloshirt made of 100% pre-shrunk, ring-spun and combed cotton. The model in grey melange is made of 90% cotton and 10% viscose.

Supplier: AGILENT

The AriaMx real-time PCR system is a fully integrated quantitative PCR amplification, detection and data analysis system.

Supplier: FRISTADS KANSAS

Gilets made from 65% polyester and 35% cotton; napped inner.

Supplier: Portwest

These thermal trousers made of 50% polyester and 50% cotton create a layer of warmth around the lower body.

Supplier: Portwest

These trousers are made of Fortis fabric consisting of 65% polyester and 35% cotton.

Supplier: SIOEN

Water- and windproof overall made of Flexothane® Classic: 100% polyamide knitting with PU coating. The durable garment offers protection against liquid chemicals.

Supplier: Portwest

The DX4 holster trouser is ergonomically designed and uses the targeted placement of dynamic 4X stretch fabrics to give maximum range of movement when working. The trouser features a high-rise back waistband with side elastication, ensuring protection in all working positions.

Supplier: FRISTADS KANSAS

Overalls made from 65% polyester and 35% cotton, with soft nap on reverse side.

Supplier: ProSci Inc.

Human epidermal growth factor receptor 2 (HER2) is a type of membrane glycoprotein, and belongs to the epidermal growth factor (EGF) receptor family. HER2 plays a key role in development, cell proliferation and differentiation. HER2 has been reported to associate with malignancy and a poor prognosis in numerous carcinomas, including breast, prostate, ovarian, lung cancers and so on. HER2 is activated by dimerization and not activated by EGF, TGF-alpha and amphiregulin. Interaction with PTK6 increases its intrinsic kinase activity.It is heterodimer with EGFR, ERBB3 and ERBB4. HER2 associates with the 5'-TCAAATTC-3' sequence in the PTGS2/COX-2 promoter and activates its transcription. It implicated in transcriptional activation of CDKN1A and the function of the protein involves STAT3 and SRC. And also it involved in the transcription of rRNA genes by RNA Pol I and enhances protein synthesis and cell growth.

Supplier: MICRONOVA

Concentrated, all-purpose cleanroom detergent is designed for use between disinfectant applications and for residue removal. Free of mobile ions, this formula is effective on most surfaces, including conductive flooring and semi conductor applications.

Supplier: SIOEN

Protective, single colour jacket made of 100% soft double-sided polyester fleece providing good cold protection. With anti-pilling treatment and stitched seams.

Supplier: FRISTADS KANSAS

Work trousers made ​​of 65% polyester and 35% cotton. With mechanical stretch and brushed inside. Material and knee pad pockets reinforced with Cordura®.

Supplier: MICRONOVA

The stainless steel Micronova BinLiner™ Stands™ are designed to work flawlessly with the BinLiners™ and similar sized bags. Securely hold a range of bin liner bags and feature two styles of open rod frames that allow ergonomic side removal of liners for simplified use.

Supplier: FRISTADS KANSAS

Work trousers made from 65% polyester and 35% cotton, in a luxury fabric. With rubber-free, elastic straps and adjustable waist.

Supplier: FRISTADS KANSAS

This robust and windproof two-colour jacket is made of 100% polyester and features a polyester lining. Ideal for people working in demanding industries.

Supplier: ProSci Inc.

PRPF19 plays a role in DNA double-strand break (DSB) repair and pre-mRNA splicing reaction. It binds double-stranded DNA in a sequence-nonspecific manner. PRPF19 acts as a structural component of the nuclear framework. It may also serve as a support for spliceosome binding and activity. It is essential for spliceosome assembly in a oligomerization-dependent manner and might also be important for spliceosome stability. It also may have E3 ubiquitin ligase activity. The PSO4 complex is required in the DNA interstrand cross-links (ICLs) repair process. Overexpression of PRPF19 might extend the cellular life span by increasing the resistance to stress or by improving the DNA repair capacity of the cells.In S. cerevisiae, Pso4 has pleiotropic functions in DNA recombination and in error-prone nonhomologous end-joining DNA repair.

Supplier: Rubbermaid Commercial Products

Safely collect waste wih touch-free closed lid containers.

Supplier: Corning

Axygen® ImpermaMat sealing mats minimize evaporation in a wide range of temperatures in PCR and storage applications. ImpermaMats are chemically resistant, reusable sealing mats, that provide a high degree of confidence.

Supplier: FRISTADS KANSAS

Cold resistant and water-repellent softshell jacket made of 100% windproof and breathable polyester stretch, Backing is made of 100% polyester microfleece. Reinforced with 100% polyamide.

Supplier: FRISTADS KANSAS

Classic style trousers made of 100% long staple FAS® cotton twill. Suitable for all kind of craftsmen. Pockets exposed to wear and tear are reinforced with 100% polyamide.

Supplier: FRISTADS KANSAS

Shirt made of 100% spunbounded cotton (single jersey), with anti-pilling treatment. The grey melange version is manufactured from 85% cotton and 15% viscose.

Supplier: SIOEN

Protective, bicoloured jacket made of 100% soft double-sided polyester fleece providing good cold protection. With anti-pilling treatment and stitched seams. Can be zipped into the rain jacket 608Z.

Supplier: FRISTADS KANSAS

Industrial jacket made of 65% polyester and 35% cotton, with soft nap on reverse side. The royal blue jacket is available with different accent and piping colours.

Supplier: AAT Bioquest

Covidyte™ IF670 is a peptide substrate containing 12 amino acid sequence (VNSTLQSGLRKM) that can be cleaved by coronavirus proteases. The dark-FRET peptide contains Tide Quencher™ 5 (TQ5) as a quencher and iFluor® 670 as a fluorescent donor on the N-and C-terminals respectively where the fluorescence of iFluor® 670 is effectively quenched by TQ5 when the peptide is intact. When the peptide is hydrolyzed by coronavirus proteases, the iFluor® 670 fragment generates significantly enhanced fluorescence since its fluorescence is no longer quenched by TQ5. The activity of coronavirus proteases can be effectively monitored by the fluorescence intensity of iFluor® 670. Covidyte™ IF670 is a robust high throughput screening tool for searching inhibitors of coronavirus proteases. Comparing to the commonly used EDANS substrates (such as Covidyte™ ED450), the iFluor® 670 substrate has much stronger and longer fluorescence that is less interfered by coloured compounds that often cause false positive hits.

Supplier: ALSICO

Functional women's trousers for the logistic sector that offer a professional look without compromising comfort. The fabric is powered by Alsiflex technology, which provides a unique combination of stretch, sustainability, and performance.

Supplier: UVP ULTRA VIOLET PRODUCTS

Cabinet c-10e cabinet only - add 4w el lamp 1 * 1 items