92764 Results for: "1-[(Benzyloxy)carbonyl]indoline-2-carboxylic+acid"

Supplier: Merck

Available with optimised 2 μm particulate silica, these UHPLC columns, based on Purospher® STAR RP-18 endcapped, are ideal for ultra-fast applications, where resolution, sensitivity and sample throughput are crucial. They are the first choice for high throughput screening and QC analyses, process monitoring, method development and LC-MS applications. Due to its balanced selectivity, Purospher® STAR RP-18 endcapped UHPLC columns cover almost all demanding separations with tailing-free chromatograms. Purospher® STAR RP-18 endcapped 3 μm columns are recommended for difficult samples where clogging and back pressure present an issue.

Supplier: Bioss

Component of a heterodimeric G-protein coupled receptor for GABA, formed by GABBR1 and GABBR2. Within the heterodimeric GABA receptor, only GABBR1 seems to bind agonists, while GABBR2 mediates coupling to G proteins. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors, such as adenylate cyclase. Signaling inhibits adenylate cyclase, stimulates phospholipase A2, activates potassium channels, inactivates voltage-dependent calcium-channels and modulates inositol phospholipid hydrolysis. Calcium is required for high affinity binding to GABA. Plays a critical role in the fine-tuning of inhibitory synaptic transmission. Pre-synaptic GABA receptor inhibits neurotransmitter release by down-regulating high-voltage activated calcium channels, whereas postsynaptic GABA receptor decreases neuronal excitability by activating a prominent inwardly rectifying potassium (Kir) conductance that underlies the late inhibitory postsynaptic potentials. Not only implicated in synaptic inhibition but also in hippocampal long-term potentiation, slow wave sleep, muscle relaxation and antinociception. Activated by (-)-baclofen, cgp27492 and blocked by phaclofen. Isoform 1E may regulate the formation of functional GABBR1/GABBR2 heterodimers by competing for GABBR2 binding. This could explain the observation that certain small molecule ligands exhibit differential affinity for central versus peripheral sites.

Supplier: Corning

These thermoconductive modules provide reproducible and standardised temperature control to biological samples while on the bench.

Supplier: OHAUS

Waterproof compact scales designed for the food industry. Features include keypad with two mechanical switches on V22PWE models and four on V22XWE models, adjustable feet, level bubble and cover with spring to protect power connector of the scale from ingress of moisture, especially when the scale is washed down. Dual LED display back and front enable two operators to work with the Valor® 2000 at the same time. Choice of scale with plastic or stainless steel housing, the models with stainless steel housing also have a check weighing application mode.

Supplier: LGC Standards PROMOCHEM

ETHYL 4-[(11RS)-8-CHLORO-11-HYDROXY-6,11 1 * 100 mg

Supplier: ProSci Inc.

ULBP1, also known as RAET1I and NKG2DL1, is a member of the ULBP/RAET1 gene family. ULBP1 plays an important role in immune responses, especially in cancer and infectious diseases, and is well-known to bind to NKG2D together with at least ULBP 2 and 3. These proteins are distantly related to major histocompatibility class I (MHC I) molecules, possessing the alpha 1 and alpha 2 Ig-like domains, but lacking the alpha 3 domain. Unlike MHC Class I, they have no capacity to bind peptide or interact with beta2-microglobulin. It can activate multiple signallling pathways in primary NK cells, gamma delta T cells, and CD8+ alpha beta T cells, resulting in the production of cytokines and chemokines.ULBP1 is expressed in wide range of tissues including heart, brain, lung, liver, bone marrow and some tumour cells, T-cells, B-cells, As an unconventional member of the MHC class I family, ULBP1 is able to interact with soluble CMV glycoprotein UL16 in CMV infected cells. The interaction with UL16 blocked the interaction with the NKG2D receptor, and thus might escape the immune surveillance. Furthermore, UL16 also causes ULBP1 to be retained in the ER and cis-Golgi apparatus so that it does not reach the cell surface. The ULBP1 regulation may have implications for development of new therapeutic strategies against cancer cells.

Supplier: Merck

A centrifugal tool for purifying and concentrating His-tagged proteins, GSH-tagged proteins and antibodies.

Supplier: MP Biomedicals

Purity: 98%1 ml = approx. 0.93 g 1 * 100 mL

Supplier: MP Biomedicals

Monohydrate Crystalline Purity: 99% 1 * 100 g

Supplier: MP Biomedicals

Trisodium Salt Monohydrate Crystalline Purity: 98% Actually a physical blend of EDTA disodium and EDTA tetrasodium. 1 * 100 g

Supplier: MP Biomedicals

Crystalline Light yellow Purity: 99% 1 * 1 g

Supplier: MP Biomedicals

Monopotassium Salt 1 * 25 mg

Supplier: MP Biomedicals

Monopotassium Salt 1 * 100 mg

Supplier: Hach

BIOTECTOR 1.8N SCHWEFELSAURE 80MG/L MN

Supplier: MP Biomedicals

Approx. 10% (w/v) 1 * 25 mL

Supplier: MP Biomedicals

Monopotassium Salt 1 * 1 g

Supplier: MP Biomedicals

Highly purified Purity: 99.5-100%1 ml = approx. 0.97 g 1 * 100 mL

Supplier: MP Biomedicals

Calcium Salt Crystalline meets or exceeds USP specifications. 1 * 100 g

Supplier: DIAGNOSTIC SYSTEMS DIASYS

GALLENSAÜREN 1X50+1X10+1X2ML

Supplier: BUCHI

Zusammensetzung 4 % Borsäure gemischt mit Sher-Indikator und eingestellt pH 4,65 +/- 0,15 1 * 5 L

Supplier: GERBER FUNKE

1,500-1,550 0.001 1 * 1 items

Supplier: EHRENSTORFER

100 µg/mL in Acetonitrile:Dimethyl sulfoxide 1 * 1 mL

Supplier: EHRENSTORFER

100 µg/mL in Acetonitrile:Dimethyl sulfoxide 1 * 1 mL

Supplier: Atago

This Master Kit is specifically for measuring vinegar and includes everything you need for easy, precise and accurate measurements. null

Supplier: THERMO SAVANT

The Thermo Scientific™ Savant™ SpeedVac™ SPD130DLX vacuum concentrator is a medium-capacity, vacuum concentrator with a modular design. It is compatible with a wide variety of solvents and offers resistance to TFA, DMSO, and other aggressive solvents used in combinatorial chemistry applications.

Supplier: LGC Standards PROMOCHEM

Standart in Hydrocarbon Oil 1 * 100 g

Supplier: Merck Millipore (Calbiochem‎)

MMP-13, PYRIMIDINE-4,6-DICARBOXYLIC ACI 1 * 1 mg

Supplier: US Biological

Crosslinking agent in immobilization of thrombogenesis-inhibiting enzymes 1 * 100 mg

Supplier: BUCHI

Needle-bar 1 * 1 items

Supplier: BUCHI

Acidproof pump 1 * 1 items