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Methanol ≥99.5% (by GC), EMPROVE® ESSENTIAL NF, Ph. Eur., BP, JPE, extra pure suitable for use as excipient, SAFC®
 :  MERCK PRODUCTION CHEMICALS
    
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Methanol ≥99.5% (by GC), EMPROVE® ESSENTIAL NF, Ph. Eur., BP, JPE, extra pure suitable for use as excipient, SAFC®
 :  MERCK PRODUCTION CHEMICALS
    
 

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  • Environmentally Preferable:
    Safer Human and Environmental Health
  • Environmental certification:
    Chem21 Solvent Selection Guide recommended after discussion

 

 

  • Assay (GC):
    ≥ 99.5 %
  • Identity (IR):
    conforms
  • Identity B (NF):
    conforms
  • Identity (JPE):
    conforms
  • Appearance:
    conforms
  • Clarity of solution:
    conforms
  • Acidity or alkalinity:
    conforms
  • Acidity:
    conforms
  • Alkalinity (as NH₃):
    ≤ 3 ppm
  • Refractive index (n 20/D):
    1.328 - 1.330
  • Density (d 20 °C/20 °C):
    0.791 - 0.793
  • Boiling range (64-65°C):
    ≥ 95 % (v/v)
  • Absorbance (at 230 nm):
    ≤ 0.150
  • Absorbance (at 250 nm):
    ≤ 0.050
  • Absorbance (at 270 nm):
    ≤ 0.020
  • Absorbance (at 290 nm):
    ≤ 0.010
  • The absorption curve is smooth:
    conforms
  • Benzene (impurity A) (GC):
    ≤ 2 ppm
  • Acetone (GC):
    ≤ 0.001 %
  • Ethanol (GC):
    ≤ 0.005 %
  • Ethanol (JPE):
    conforms
  • Related substances (GC):
    conforms
  • Residual solvents class 3 (ICH Q3C):
    < 0.5
  • Other residual solvents (ICH Q3C):
    excluded by manufacturing process
  • Al (Aluminium)*:
    ≤ 0.05 ppm
  • Cu (Copper)*:
    ≤ 0.05 ppm
  • Zn (Zinc)*:
    ≤ 0.05 ppm
  • Heavy metals:
    conforms
  • Aldehydes and Acetone (as acetone):
    ≤ 0.003 %
  • Aldehyde and other foreign reducing substances:
    conforms
  • Reducing substances:
    conforms
  • Readily oxidizable substances:
    conforms
  • Readily carbonizable substances:
    conforms
  • Readily carbonizable substances (JPE):
    conforms
  • Evaporation residue:
    ≤ 0.0010 %
  • Water:
    ≤ 0.10 %

 

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