Standard samples for HPLC System Qualification.

In order to facilitate this instrument qualification in the HPLC laboratory Merck Millipore and Avantor have developed the LiChroTest® products. These enable time saving Operational and Performance Qualification to be performed routinely and according to standardised methods.

The quality of analytical results is principally determined by the correct functioning of the analytical instruments employed. For this reason, the various quality assurance systems as well as the FDA require analytical instruments to be subjected to periodic qualification. Therefore, before starting a series of analyses, you first should establish whether your HPLC system meets with your requirements. These 'Operational Qualification' (OQ) and 'Performance Qualification' (PQ) steps involve tests of the different modules on their specifications and a check on the entire system using a real application relevant to the laboratory-specific requirements.