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- Pk:1 KIT
- Description:Rheumatoid factor (RF) concentrate, human
- Environmentally Preferable:
- Storage temperature:Stored at −20 °C
Rheumatoid arthritis (RA) is a chronic inflammatory disease of unknown etiology. Rheumatoid arthritis is a systemic disease characterised by chronic proliferation and inflammation of joint cartilage and supporting structures.
- Source: Human plasma
- Form: Supplied as a liquid in 20 mM sodium phosphate, 0,5 M sodium chloride, 0,02% proclin 300, pH 7,2
- Appearance: Yellow to orange, clear to hazy liquid
- Activity: ≥25000 IU/ml
- Shipping temperature: Blue ice
RA is mainly defined by clinical criteria, in which systematic pathogenetic studies have been hampered by doubts about the presence of common pathogenetic mechanisms and the relative lack of unique laboratory findings. IgG rheumatoid factor has been reported to be present in sera of patients with rheumatoid arthritis both with and without IgM rheumatoid factor activity.
This is highly concentrated for minimum volume additions for control/calibrator manufacturing versus plasma or serum, saving money on other material components. Native-sourced, mimicking elevated RF human donor samples during assay interference studies.
Ideal for spike-interference studies in assay development and validation.