Specifications
- Antigen name:VHH
- Clonality:Monoclonal
- Clone:45H8
- Conjugation:HRP (Horseradish Peroxidase)
- ELISA:Yes
- Host:Rabbit
- Isotype:IgG
- Cross adsorption:It has no cross-reactivity with mouse, rat, rabbit, or goat immunoglobulins
- Form:Liquid
- Storage buffer:Supplied in PBS (pH 7,2), containing 10 mg/ml BSA, 0,01% thimerosal and 50% glycerol
- Storage temperature:Store at −20 °C. This product is stable for 1 year upon receipt, when handled and stored as instructed
- Concentration:0,5 mg/ml
- Immunogen:VHH antibody
- Pack type:Vial
- Pk:200 µl
Specifications
About this item
A camelid single-domain antibody (sdAb, called Nanobody by Ablynx, the developer) is a peptide chain of about 110 amino acids long, comprising one variable domain of a heavy-chain antibody, these are called VHH fragments. Like a whole antibody, it is able to bind selectively to a specific antigen. Single-domain antibodies allow a broad range of applications in biotechnical as well as therapeutic uses due to their small size, simple production, and high affinity. However, their sequences may increase the risk of immunogenicity and anti-drug antibody (ADA) development in humans, and thus, sdAbs are routinely humanised during development.
- MonoRab™ technology guarantees high affinity: Kd ~10 to 11 M
- No cross reactivity with other species
- Specific to camelid IgG2 and IgG3
- Recognise conformational epitopes of the VHH domain
- Recognise both camelid and humanised VHHs
GenScript has developed a series of rabbit monoclonal (MonoRab) anti-VHH antibodies to facilitate your research of VHHs. Our anti-VHH antibodies recognise conformational epitopes of the VHH domain of camelid lgG2 and lgG3 subclasses. It is not necessary to add a tag to VHH for detection anymore.
Type:
Antigen: VHH
Clonality: Monoclonal
Clone: 45H8
Conjugation: HRP (Horseradish Peroxidase)
Epitope:
Host: Rabbit
Isotype: IgG
Reactivity: