Specifications
- Antibody type:Primary
- Antigen name:CD4 molecule
- Antigen symbol:CD4
- Clonality:Monoclonal
- Clone:RPA-T4
- Conjugation:PerCP (Peridinin-Chlorophyll Protein Complex)/Cy5.5®
- Flow cytometry:Yes
- Host:Mouse
- Isotype:IgG1 kappa
- Reactivity:Human
- Cross adsorption:No
- Form:liquid
- Gene ID:P01730
- Antigen synonyms:CD4
- Storage buffer:Phosphate-buffered aqueous solution, ≤0,09% Sodium azide, may contain carrier protein/stabiliser, ph 7,2.
- Storage temperature:The product should be stored undiluted at 4 °C and should be protected from prolonged exposure to light. Do not freeze.
- Shipping temperature:4 °C
- Purification:The monoclonal antibody was purified utilizing affinity chromatography and unreacted dye was removed from the product.
- Pk:100 Tests
Specifications
About this item
The RPA-T4 monoclonal antibody specifically binds to the CD4 receptor for the human immunodeficiency virus (HIV). CD4 is a 59 kDa single-chain transmembrane glycoprotein that expressed on the surface of most of the thymocytes, T-helper cells, and in low levels on monocytes and macrophages. CD4 is a co-receptor in the antigen-induced T cell activation, together with the MHC class II. The RPA-T4 antibody is capable of blocking HIV binding and inhibiting syncytium formation, by binding to the D1 domain of the CD4 antigen. The OKT4 and the RPA-T4 monoclonal antibodies recognize different epitopes of CD4 and they do not exhibit cross-block binding.
Type: Primary
Antigen: CD4
Clonality: Monoclonal
Clone: RPA-T4
Conjugation: PerCP (Peridinin-Chlorophyll Protein Complex)/Cy5.5®
Epitope:
Host: Mouse
Isotype: IgG1 kappa
Reactivity: Human