- Antibody type:Primary
- Antigen name:Asialoglycoprotein Receptor 2
- Antigen symbol:ASGR2
- Clonality:Monoclonal
- Clone:OTI2A12
- Conjugation:Unconjugated
- Host:Mouse
- Isotype:IgG2b
- Reactivity:Human
- Western blot:Yes
- Environmentally Preferable:
- Format:Azide and BSA free
- Antigen synonyms:ASGR2|Hepatic lectin H2|ASGP-R2|ASGP-R 2|HL-2|HBxAg-binding protein|CLEC4H2FLJ60040|C-type lectin domain family 4 member H2|asialoglycoprotein receptor 2|ASGPR2|CLEC4H2|ASGPR 2|HBXBP
- Purity:Immunogen affinity purified
- Storage buffer:Lyophilized from PBS (pH 7,3) with 8% Trehalose
- Molecular weight:35 kDa
- Storage temperature:Store at −20 °C. Avoid freeze-thaw cycles.
- Concentration:LYOPH
- Immunogen:Full length human recombinant protein of human ASGR2 (NP_001172) produced in HEK293T cell
- Tested applications:WB, IHC
- Pk:100 µG
Asialoglycoprotein Receptor 2 is a transmembrane protein that plays a critical role in serum glycoprotein homeostasis by mediating the endocytosis and lysosomal degradation of plasma glycoproteins in which the terminal sialic acid residue on their complex carbohydrate moieties has been removed.
It is expressed exclusively in hepatic parenchymal cells and calcium is required for ligand binding. Asialoglycoprotein Receptor 2 may facilitate hepatic infection by multiple viruses including hepatitis B, and is also a target for liver-specific drug delivery. Asialoglycoprotein Receptor 2 is involved in hepatitis B, hepatitis C, liver cirrhosis, hepatocellular carcinoma, nephropathy, leukaemia, urethritis, autoimmune hepatitis, alcoholic liver cirrhosis, and jaundice.
Dilutions:
Immunohistochemistry 1:150
Immunohistochemistry-Paraffin 1:150
Western Blot 1:4000
Type: Primary
Antigen: ASGR2
Clonality: Monoclonal
Clone: OTI2A12
Conjugation: Unconjugated
Epitope:
Host: Mouse
Isotype: IgG2b
Reactivity: Human