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Anti-DRIP130/CRSP130 Rabbit Polyclonal Antibody (Alexa Fluor® 750)
Anti-DRIP130/CRSP130 Rabbit Polyclonal Antibody (Alexa Fluor® 750)
Catalog # BOSSBS-13032R-A750
Supplier:  Bioss
Anti-DRIP130/CRSP130 Rabbit Polyclonal Antibody (Alexa Fluor® 750)
Catalog # BOSSBS-13032R-A750
Supplier:  Bioss

Specifications

  • Antibody type:
    Primary
  • Antigen name:
    DRIP130/CRSP130
  • Clonality:
    Polyclonal
  • Conjugation:
    Alexa Fluor® 750
  • Host:
    Rabbit
  • ImmunoChemistry:
    Yes
  • ImmunoFluorescence:
    Yes
  • Isotype:
    IgG
  • Western blot:
    Yes
  • Epitope:
    401-500/1368
  • Form:
    Liquid
  • Gene ID:
    9439
  • Antigen synonyms:
    MED 23|CRSP 3|MED23_HUMAN|SUR2|CRSP133|Transcriptional coactivator CRSP130|Transcriptional co activator CRSP 130|Vitamin D3 receptor interacting protein|Vitamin D3 receptor-interacting protein complex 130 kDa component|133 kDa transcriptional co activator|ARC130|CRSP 130|ARC 130|Vitamin D3 receptor interacting protein complex 130 kDa component|CRSP complex subunit 3|Activator-recruited cofactor 130 kDa component|CRSP 133|130 kDa transcriptional co activator|Mediator of RNA polymerase II transcription subunit 23|KIAA1216|CRSP130|Cofactor required for Sp1 transcriptional activation subunit 3|CRSP3 protein|DKFZp434H0117|Cofactor required for Sp1 transcriptional activation subunit 3 130kDa|Activator recruited cofactor 130 kDa component|Mediator complex subunit 23|CRSP3|hSur-2|Cofactor required for Sp1 transcriptional activation subunit 3 130kDa mediator|Transcriptional co activator CRSP130|DRIP 130|DRIP130|SUR 2|CRSP 130 kD subunit|MED23|Protein sur-2 homolog
  • Modification:
    Unmodified
  • Storage buffer:
    Aqueous buffered solution containing 0,01M TBS (pH 7,4) with 1% BSA, 0,03% Proclin300 and 50% Glycerol.
  • Molecular weight:
    156 kDa
  • Storage temperature:
    Store at −20 °C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
  • Concentration:
    1 µg/µl
  • Shipping temperature:
    4 °C
  • Immunogen:
    KLH conjugated synthetic peptide derived from human DRIP130/CRSP130
  • Tested applications:
    ICC
  • Purification:
    Purified by Protein A
  • Pack type:
    Vial
  • Pk:
    100 µl

Specifications

About this item

In mammalian cells, transcription is regulated in part by high molecular weight coactivating complexes that mediate signals between transcriptional activators and RNA polymerase (1). These complexes include CRSP (for cofactor required for Sp1 activation), which is required, in conjunction with TAFIIs, for transcriptional activation by Sp1 (2). CRSP is ubiquitously expressed in various tissues and functions as a multimeric complex that consists of nine distinct subunits (3). Several members of the CRSP family share sequence similarity with multiple components of the yeast transcriptional mediator proteins, including CRSP150, which is related to yeast Rgr1, and CRSP70, which is similar to the elongation factor TFIIS (4). CRSP77 and CRSP150 are also related to proteins within the putative murine mediator complex, while CRSP130 and CRSP34 are largely unrelated to either murine or yeast proteins (2,5). CRSP subunits also associate with larger multimeric coactivaor complexes, including ARC/DRI, which binds directly to SREBP and nuclear hormone receptors to facilitate transcription, and with NAT, a polymerase II-interacting complex that represses activated transcription (6,7).

Type: Primary
Antigen: DRIP130/CRSP130
Clonality: Polyclonal
Clone:
Conjugation: ALEXA FLUOR® 750
Public Immunogen Range: 401-500/1368
Host: Rabbit
Isotype: IgG
Reactivity: