Human Recombinant IGF-I (from E. coli)

Insulin-like growth factor I (IGF-I) is a growth factor that is produced by the liver. IGF-1 production is stimulated by growth hormone (GH). IGF-I binds the insulin-like growth factor 1 receptor (IGF1R) and the insulin receptor to stimulate systemic body growth. IGF-I is one of the most potent activators of the AKT signaling pathway, which stimulates cell proliferation and inhibits programmed cell death. Mature human IGF-I is 100% homologous to bovine and porcine IGF-1 proteins.

High Quality
Low Endotoxin
Affordable

A COA is supplied with each product shipped detailing purity, formulation, biological activity, endotoxin levels, reconstitution instructions and recommended storage conditions. This product is for research use only and is not for use in humans.

: For research use only.

Coniugazione:
Non coniugato
Protein function:
Cytokine
Protein/peptide type:
Recombinant
Sorgente luminosa:
E. coli
Specie:
Human
Condizioni di conservazione:
–20 °C
Contenuto di endotossine:
Endotoxin LAL (EU/µg) ≤0,1
Attività biologica:
Bioactivity assay: Human breast cancer cell line MCF-7, ED50 ≤1,5 ng/ml, Bioactivity ≥6,7×10⁵ units/mg
ID gene:
P05019
Ricostituzione:
Sterile water at 0.1 mg/ml
Privo di endotossine:
N
Senza corriere:
Y
Protease-free:
N
Senza animali:
N
Protein synonyms:
mechano growth factor|IGF-IA|Somatomedin C
Protein/peptide name:
IGF-I
Purezza:
≥95%
Peso molecolare:
7,7 kDa
Sequenza:
GPETLCGAEL VDALQFVCGD RGFYFNKPTG YGSSSRRAPQ TGIVDECCFR SCDLRRLEMY CAPLKPAKSA
Livello di endotossine:
Low
Formulazione:
0,1% Trifluoroacetic Acid (TFA)
Esente da nucleasi:
N
Grado:
RUO
Temperatura di spedizione:
RT
Applicazioni testate:
Bioassay