Anti-MCL1 Rabbit Polyclonal Antibody

Mcl-1 is a member of the Bcl-2 family that possesses anti-apoptotic activity. Mcl-1 is an immediate-early gene activated by the GMCSF as well as IL-3 signaling pathways and plays an important role in the viability response of these cytokines. Similar to all Bcl-2 family members, Mcl-1 contains BH1, BH2, and BH3 domains; however, unlike other members of this family, Mcl-1 has an extended N-terminal domain rich in PEST sequences, which probably accounts for the short half-life of this protein.

• For Immunofluorescence, Western Blot

Recognizes human, dog, guinea pig, monkey, pig and rabbit Mcl-1. Detects a band of ~42/43kDa by Western blot.

Type: Primary
Antigen: MCL1
Clonality: Polyclonal
Clone:
Conjugation:
Epitope:
Host: Rabbit
Isotype:
Reactivity: Human