Specifications
- Pk:50 µG
- Protein/peptide type:Recombinant
- Source:Cells
- Species:Human
- Environmentally Preferable:
- Tag sequence:C-6 His tag
- Storage conditions:Lyophilized protein should be stored at −20 °C, though stable at room temperature for 3 weeks. Reconstituted protein solution can be stored at 4-7 °C for 2-7 days. Aliquots of reconstituted samples are stable at −20 °C for 3 months.
- Protein synonyms:Phagocytic Glycoprotein I|MDU2|HUTCH-I|Epican|LHR|CD44|MIC4|ECMR-III|Phagocytic Glycoprotein 1|CDw44|PGP-I|CD44 Antigen|Hyaluronate Receptor|Hermes Antigen|Heparan Sulfate Proteoglycan|Extracellular Matrix Receptor III|MDU3|GP90 Lymphocyte Homing/Adhesion Receptor|PGP-1
- Protein/peptide name:CD44
- Purity:> 95% as determined by reducing SDS-PAGE
- Molecular weight:23.1 kD
- Sequence:Gln21-Pro220
- Formulation:Lyophilized from a 0.2 um filtered solution of 20mM PB, 150mM NaCl, pH 7.2. Always centrifuge tubes before opening. Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100 ug/ml. Dissolve the Lyophilized protein in ddH2O. Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
- Tested applications:For Biological Assays
Specifications
About this item
CD44 is a cell-surface receptor for hyaluronic acid and also interacts with other ligands, such as osteopontin, collagens, and matrix metalloproteinases. A large number of CD44 isoforms can be generated by the insertion of different combinations of at least nine exons. Increased CD44 antigen is associated with relapses in non-small cell lung cancers. Furthermore, an increasing quantity of evidence suggests that CD44 has various functions related to inflammatory disease. CD44 deficiency induces severe liver injury. CD44-hyaluronate mediates in lymphocyte T and monocyte adhesion to the endothelium, stimulates proinflammatory cytokine release from macrophages and participates in dedifferentiation phenotype of smooth muscle cells from contractile state to synthetic one.
- This recombinant protein can be used for biological assays. For research use only.
Fusion-Tag: C-6 His tag