FUNCTION: Monokine with inflammatory and chemokinetic properties. Binds to CCR5. One of the major HIV-suppressive factors produced by CD8+ T cells. Recombinant MIP-1-beta induces a dose-dependent inhibition of different strains of HIV-1, HIV-2, and simian immunodeficiency virus (SIV). The processed form MIP-1-beta(3-69) retains the abilities to induce down-modulation of surface expression of the chemokine receptor CCR5 and to inhibit the CCR5-mediated entry of HIV-1 in T cells. MIP-1-beta(3-69) is also a ligand for CCR1 and CCR2 isoform B.

Small inducible cytokine A4 antibody can be used for the detection of Small inducible cytokine A4 by ELISA and Western Blot, may also work for ICC and IHC.

Phosphate-Buffered Saline. No preservatives added.

Phosphate-Buffered Saline. No preservatives added.

Aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Type:
Antigen: CCL4
Clonality: Polyclonal
Clone:
Conjugation: Unconjugated
Epitope:
Host: Chicken
Isotype: IgG
Reactivity: Human