- Antibody type:Primary
- Antigen name:Src Kinase Associated Phosphoprotein 2
- Antigen symbol:SCAP2
- Clonality:Polyclonal
- Conjugation:FITC (Fluorescein Isothiocyanate)
- Host:Rabbit
- ImmunoChemistry:Yes
- Isotype:IgG
- Reactivity:Human,Rat,Mouse
- Cross adsorption:No
- Form:liquid
- Antigen synonyms:Retinoic acid-induced protein 70|MGC33|SAPS|skap2|Src kinase-associated phosphoprotein 55-related protein|src kinase associated phosphoprotein of 55 related protein|SKAP-55HOM|SKAP-HOM|RA70|Src family associated phosphoprotein 2|Src-associated adapter protein with PH and SH3 domains.|SKAP55 homolog|Src kinase-associated phosphoprotein 2|Src family-associated phosphoprotein 2|Pyk2/RAFTK-associated protein|SKAP2_HUMAN|Src associated adaptor protein|SKAP55R|Pyk2/RAFTK associated protein|PRAP|Fyn associated phosphoprotein SKAP55 homologue|MGC10411
- Storage buffer:Aqueous buffered solution containing 100ug/ml BSA, 50% glycerol and 0.09% sodium azide. Store at 4°C for 12 months.
- Storage temperature:Store at 4°C for 12 months
- Concentration:1 μg/μl
- Shipping temperature:4°C
- Purification:Purified by Protein A
- Pk:100 µl
Fyb (Fyn binding protein) and the anchoring proteins SKAP55 and SKAP55-R (SKAP55-related protein) associate with the tyrosine kinase p59fyn. SKAP55 and SKAP55-R bind to Fyb through their SH3 domains and function as substrates for p59Fyn in resting T cells. SKAP55 contains an N-terminal pleckstrin homology domain and a C-terminal SH3 domain binding motif of adjacent arginine and lysine residues followed by tandem tyrosines (i.e. RKxxYxxY). SKAP55-R, similar in overall structure to SKAP55, contains a coiled-coil N-terminal domain. SKAP55 associates with SLAP-130, another component of the Fyn complex, which plays a role in the regulation of signaling events initiated by lymphocyte antigen receptors leading up to T cell activation. The human SKAP55 gene maps to chromosome 17q21.32 and encodes a 359 amino acid protein.
Recommended Dilutions: IF(IHC-P): 1:50-200
Type: Primary
Antigen: SCAP2
Clonality: Polyclonal
Clone:
Conjugation: FITC (Fluorescein Isothiocyanate)
Epitope:
Host: Rabbit
Isotype: IgG
Reactivity: Human, Mouse, Rat