The selectivity offered by ZIC®-HILIC is suitable for a wide variety of molecules containing hydrophilic or ionisable functional groups. This includes compounds such as carbohydrates, metabolites, acids and bases, organic and inorganic ions, metal complexes, amino acids, peptides, protein digests, plant and cell extracts, plus much more. Such compounds are normally characterised by a small or negative LogP value and have poor retention on reversed-phase columns.

• Straightforward separation of polar and hydrophilic compounds
• Orthogonal selectivity compared to reversed-phase
• High density-bonded sulphobetaine zwitterionic stationary phase
• Low cost per analysis due to robust stationary phase

* HILIC = Hydrophilic Interaction Liquid Chromatography. *LogP = Octanol-water partition coefficient.