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Recognizes a 27 kDa protein, identified as the p27Kip1, a cell cycle regulatory mitotic inhibitor. Its epitope spans between aa 83-204 of p27. It is highly specific and shows no cross-reaction with other related mitotic inhibitors. p27Kip1 functions as a negative regulator of G1 progression and has been proposed to function as a possible mediator of TGF- induced G1 arrest. p27Kip1 is a candidate tumor suppressor gene. This MAb co-precipitates cdk4 in complex p27Kip1 and is excellent for staining of formalin-fixed tissues.
Type: Primary
Antigen: CDKN1B
Clonality: Monoclonal
Clone: DCS-72.F6
Conjugation: Biotin
Epitope:
Host: Mouse
Isotype: IgG1 kappa
Reactivity: Human, Monkey, Mouse, Rat
Specifiche
- Catalog No:
- BNCB0771-100
- BNCB0771-500
- Antigen symbol:
- CDKN1B
- CDKN1B
- Antigen name:
- Cyclin-dependent kinase inhibitor 1B
- Cyclin-dependent kinase inhibitor 1B
- Antigen synonyms:
- CDKN1B|CDKN4|KIP1|Cyclin-dependent kinase inhibitor p27 Kip1|MEN1B|Cyclin Dependent Kinase Inhibitor 1B|MEN4
- CDKN1B|CDKN4|KIP1|Cyclin-dependent kinase inhibitor p27 Kip1|MEN1B|Cyclin Dependent Kinase Inhibitor 1B|MEN4
- Antibody type:
- Primary
- Primary
- Clonality:
- Monoclonal
- Monoclonal
- Conjugation:
- Biotin
- Biotin
- Clone:
- Clone DCS-72.F6
- Clone DCS-72.F6
- Reactivity:
- Monkey, Human, Rat, Mouse
- Monkey, Human, Rat, Mouse
- Host:
- Mouse
- Mouse
- Gene ID:
- 238990
- 238990
- Isotype:
- IgG1 kappa
- IgG1 kappa
- Western blot:
- Yes
- Yes
- ImmunoChemistry:
- Yes
- Yes
- ImmunoFluorescence:
- Yes
- Yes
- Concentration:
- 0,1 mg/ml
- 0,1 mg/ml
- Storage buffer:
- PBS/0,1% BSA/0,05% azide
- PBS/0,1% BSA/0,05% azide
Specifiche
Nome del fornitore: HEATHROW
Nome del fornitore: VWR Chemicals
Nome del fornitore: Merck
Nome del fornitore: VWR Chemicals
Nome del fornitore: VWR Collection
Nome del fornitore: VWR Collection
Nome del fornitore: Merck
Nome del fornitore: VWR Collection
Nome del fornitore: VWR Collection
Nome del fornitore: VWR Chemicals
Nome del fornitore: VWR Chemicals
Nome del fornitore: KIMBERLY CLARK
Nome del fornitore: VWR Collection