- Antibody type:Primary
- Antigen name:Extracellular signal-regulated kinase 5
- Antigen symbol:ERK5
- Clonality:Polyclonal
- Conjugation:Unconjugated
- Host:Rabbit
- ImmunoChemistry:Yes
- Isotype:IgG
- Reactivity:Human,Rat,Mouse
- Western blot:Yes
- Cross adsorption:No
- Form:liquid
- Antigen synonyms:ERK-5|BMK-1.|Extracellular signal-regulated kinase 5|MAP kinase 7|MAPK7|MAPK 7|PRKM7|BMK1|Mitogen-activated protein kinase 7|Big MAP kinase 1
- Modification:Thr219 + Tyr221
- Storage buffer:Aqueous buffered solution containing 100 μg/ml BSA, 50% glycerol and 0,09% sodium azide. Store at –20 °C for 12 months.
- Storage temperature:Store at –20 °C for 12 months
- Concentration:1 μg/μl
- Shipping temperature:4 °C
- Purification:Purified by Protein A
- Size:100 μg
- Pk:100 µl
The protein encoded by this gene is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. This kinase is specifically activated by mitogen-activated protein kinase kinase 5 (MAP2K5/MEK5). It is involved in the downstream signaling processes of various receptor molecules including receptor type kinases, and G protein-coupled receptors. In response to extracelluar signals, this kinase translocates to cell nucleus, where it regulates gene expression by phosphorylating, and activating different transcription factors. Four alternatively spliced transcript variants of this gene encoding two distinct isoforms have been reported. [provided by RefSeq, Jul 2008]
WB(1:100-1000), IHC-P(1:100-500), IF(IHC-P)(1:50-200)
Type: Primary
Antigen: ERK5
Clonality: Polyclonal
Clone:
Conjugation: Unconjugated
Epitope:
Host: Rabbit
Isotype: IgG
Reactivity: Human, Mouse, Rat