Anti-HTRA2 Rabbit Polyclonal Antibody (Alexa Fluor® 350)

Catalog # BOSSBS-1271R-A350

Supplier: Bioss

Catalog # BOSSBS-1271R-A350

Supplier: Bioss

Specifications

Antibody type:
Primary
Antigen name:
High Temperature Requirement Protein A2
Antigen symbol:
HTRA2
Clonality:
Polyclonal
Conjugation:
Alexa Fluor® 350
Host:
Rabbit
ImmunoChemistry:
Yes
Isotype:
IgG
Reactivity:
Human,
Rat,
Mouse
Cross adsorption:
No
Form:
liquid
Gene ID:
27429
Antigen synonyms:
mitochondrial|Serine protease HTRA2|OMI|HtrA2|PRSS25|PARK13|High temperature requirement protein A2
Storage buffer:
Aqueous buffered solution containing 100ug/ml BSA, 50% glycerol and 0.09% sodium azide. Store at 4°C for 12 months.
Storage temperature:
Store at 4°C for 12 months
Concentration:
1 μg/μl
Shipping temperature:
4°C
Purification:
Purified by Protein A
Pk:
100 µl

Specifications

About this item

Serine protease that shows proteolytic activity against a non-specific substrate beta-casein. Promotes or induces cell death either by direct binding to and inhibition of BIRC proteins(also called inhibitor of apoptosis proteins, IAPs), leading to an increase in caspase activity, or by a BIRC inhibition-independent, caspase-independent and serine protease activity-dependent mechanism. Isoform 2 seems to be proteolytically inactive. [CATALYTIC ACTIVITY] Cleavage of non-polar aliphatic amino-acids at the P1 position, with a preference for Val, Ile and Met. At the P2 and P3 positions, Arg is selected most strongly with a secondary preference for other hydrophilic residues. [SUBUNIT] Homotrimer. Interacts with MXI2. The mature protein, but not the precursor, binds to BIRC2, BIRC3 and XIAP.

Recommended Dilutions: IF(IHC-P): 1:50-200

Type: Primary
Antigen: HTRA2
Clonality: Polyclonal
Clone:
Conjugation: Alexa Fluor® 350
Epitope:
Host: Rabbit
Isotype: IgG
Reactivity: Human, Mouse, Rat