Antibody glycosylation analysis – the common, the accurate and the smart way
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The webinar will present methods to analyze glycosylation of antibodies. As glycosylation of the Fc region of a therapeutic antibody influences its mode of action, glycan patterns are frequently analyzed:
- In development to monitor success of Fc-optimization
- In upstream development to screen the influence of production conditions on glycosylation
- During manufacturing to monitor the process
- In the final product for quality control, stability testings and comparisons between production lots
HPLC-based methods are presented that analyze Fc glycosylation and its functional consequences. We compare them and clarify which method is suitable for which question.
For more information, please contact us at [email protected]
Presented by:
Andrea Krumm
Andrea Krumm studied biotechnology before gaining a PhD in cell- and cancer-biology. After four years as an applications specialist for optical analytical devices used in academic and pharmaceutical research, she joined Tosoh Bioscience GmbH in 2020 as a product manager for analytical columns. As such she is responsible for gathering customer requirements, application areas and addressing these with new and existing products of the analytical columns line.